The impact of D614G mutation of SARS-COV-2 on the efficacy of anti-viral drugs: A comparative molecular docking and molecular dynamics study
D614G is one of the most reported mutations in the spike protein of SARS-COV-2 that has
altered some crucial characteristics of coronaviruses, such as rate of infection and binding …
altered some crucial characteristics of coronaviruses, such as rate of infection and binding …
In silico SELEX screening and statistical analysis of newly designed 5mer peptide-aptamers as Bcl-xl inhibitors using the Taguchi method
Drug development for cancer treatment is a complex process that requires special efforts.
Targeting crucial proteins is the most essential purpose of drug design in cancers. Bcl-xl is …
Targeting crucial proteins is the most essential purpose of drug design in cancers. Bcl-xl is …
Modeling and affinity maturation of an anti-CD20 nanobody: a comprehensive in-silico investigation
B-cell Non-Hodgkin lymphomas are the malignancies of lymphocytes. CD20 is a membrane
protein, which is highly expressed on the cell surface of the B-cells in NHL. Treatments using …
protein, which is highly expressed on the cell surface of the B-cells in NHL. Treatments using …
Tracing the pathways and mechanisms involved in the anti-breast cancer activity of glycyrrhizin using bioinformatics tools and computational methods
A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
A complete investigation to understand the pathways that could be affected by glycyrrhizin
(licorice), as anti-breast cancer (BC) agent, has not been performed to date. This study aims …
(licorice), as anti-breast cancer (BC) agent, has not been performed to date. This study aims …
Construction of Bio-conjugated nano-vesicles using non-ionic surfactants for targeted drug delivery: A computational supported experimental study
Introduction Targeted delivery of drugs to the brain is a complicated activity. This
complication is caused by the blood–brain barrier (BBB). Interestingly, there are various …
complication is caused by the blood–brain barrier (BBB). Interestingly, there are various …
Evaluation of the FDA-approved kinase inhibitors to uncover the potential repurposing candidates targeting ABC transporters in multidrug-resistant cancer cells: an in …
A Poustforoosh, F Moosavi - Journal of Biomolecular Structure and …, 2024 - Taylor & Francis
Multiple drug resistance (MDR) is characterized by the resistance of cancer cells to a broad
spectrum of anticancer drugs. The main mechanism underlying the MDR phenotype is the …
spectrum of anticancer drugs. The main mechanism underlying the MDR phenotype is the …
Cutaneous pharmacokinetics of topically applied novel dermatological formulations
Novel formulations are developed for dermatological applications to address a wide range
of patient needs and therapeutic challenges. By pushing the limits of pharmaceutical …
of patient needs and therapeutic challenges. By pushing the limits of pharmaceutical …
Investigation on the mechanisms by which the herbal remedies induce anti-prostate cancer activity: uncovering the most practical natural compound
A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
Prostate cancer (PCa) is one of the most reported cancers among men worldwide. Targeting
the essential proteins associated with PCa could be a promising method for cancer …
the essential proteins associated with PCa could be a promising method for cancer …
Investigation on the structural and dynamical properties of cationic, anionic, and catanionic niosomes as multifunctional controlled drug delivery system for …
A Poustforoosh - Colloids and Surfaces A: Physicochemical and …, 2024 - Elsevier
Background Niosomes are versatile nanocarriers for therapeutic compounds, and optimizing
their structures via ionic surfactants can enhance their functionality considerably. Catanionic …
their structures via ionic surfactants can enhance their functionality considerably. Catanionic …
Removal of safranin O from wastewater using Streptomyces griseobrunneus dead biomass and in silico calculations
MS Çelik, N Kütük, AF Yenidünya, S Çetinkaya… - Biomass Conversion …, 2024 - Springer
Environmental pollution with the dye produced by the textile industry causes a serious
problem worldwide. The aim of the study is to use the environmentally friendly and low-cost …
problem worldwide. The aim of the study is to use the environmentally friendly and low-cost …