Msx homeobox gene family and craniofacial development

S Alappat, ZY Zhang, YP Chen - Cell research, 2003 - nature.com
Vertebrate Msx genes are unlinked, homeobox-containing genes that bear homology to the
Drosophila muscle segment homeobox gene. These genes are expressed at multiple sites …

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu… - Science, 2017 - science.org
INTRODUCTION Nearly all cells in the human body share the same primary genome
sequence consisting of four nucleotide bases. One of the bases, cytosine, is commonly …

[HTML][HTML] Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites

MB Noyes, RG Christensen, A Wakabayashi… - Cell, 2008 - cell.com
We describe the comprehensive characterization of homeodomain DNA-binding specificities
from a metazoan genome. The analysis of all 84 independent homeodomains from D …

[HTML][HTML] Functional specificity of a Hox protein mediated by the recognition of minor groove structure

R Joshi, JM Passner, R Rohs, R Jain, A Sosinsky… - Cell, 2007 - cell.com
The recognition of specific DNA-binding sites by transcription factors is a critical yet poorly
understood step in the control of gene expression. Members of the Hox family of …

[图书][B] Structure in protein chemistry

J Kyte - 2006 - books.google.com
The second edition of Structure in Protein Chemistry showcases the latest developments
and innovations in the field of protein structure analysis and prediction. The book begins by …

Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein–DNA binding

TP Chiu, S Rao, RS Mann, B Honig… - Nucleic acids …, 2017 - academic.oup.com
Protein–DNA binding is a fundamental component of gene regulatory processes, but it is still
not completely understood how proteins recognize their target sites in the genome. Besides …

The invention of WUS-like stem cell-promoting functions in plants predates leptosporangiate ferns

J Nardmann, W Werr - Plant Molecular Biology, 2012 - Springer
The growth of land plants depends on stem cell-containing meristems which show major
differences in their architecture from basal to higher plant species. In Arabidopsis, the stem …

Insights into DNA solvation found in protein-DNA structures

WK Olson, Y Li, MO Fenley - Biophysical Journal, 2022 - cell.com
The proteins that bind double-helical DNA present various microenvironments that sense
and/or induce signals in the genetic material. The high-resolution structures of protein-DNA …

Heteronuclear NMR Spectroscopy for Lysine NH3 Groups in Proteins:  Unique Effect of Water Exchange on 15N Transverse Relaxation

J Iwahara, YS Jung, GM Clore - Journal of the American Chemical …, 2007 - ACS Publications
In this paper, we present a series of heteronuclear NMR experiments for the direct
observation and characterization of lysine NH3 groups in proteins. In the context of the …

DNA binding analysis of rare variants in homeodomains reveals homeodomain specificity-determining residues

KH Kock, PK Kimes, SS Gisselbrecht, S Inukai… - Nature …, 2024 - nature.com
Homeodomains (HDs) are the second largest class of DNA binding domains (DBDs) among
eukaryotic sequence-specific transcription factors (TFs) and are the TF structural class with …