Current understanding of the pathogenesis of dengue virus infection

P Bhatt, SP Sabeena, M Varma, G Arunkumar - Current microbiology, 2021 - Springer
The pathogenesis of dengue virus infection is attributed to complex interplay between virus,
host genes and host immune response. Host factors such as antibody-dependent …

Dengue virus infection: a tale of viral exploitations and host responses

N Nanaware, A Banerjee, S Mullick Bagchi, P Bagchi… - Viruses, 2021 - mdpi.com
Dengue is a mosquito-borne viral disease (arboviral) caused by the Dengue virus. It is one
of the prominent public health problems in tropical and subtropical regions with no effective …

Thrombocytopenia in dengue: interrelationship between virus and the imbalance between coagulation and fibrinolysis and inflammatory mediators

EL Azeredo, RQ Monteiro… - Mediators of …, 2015 - Wiley Online Library
Dengue is an infectious disease caused by dengue virus (DENV). In general, dengue is a
self‐limiting acute febrile illness followed by a phase of critical defervescence, in which …

Intrinsic ADE: the dark side of antibody dependent enhancement during dengue infection

R Narayan, S Tripathi - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
Dengue fever is an Aedes mosquito-borne illness caused by any one of the four different
dengue virus (DENV) serotypes (1–4) and manifests in the form of symptoms ranging from …

Pathogenesis of vascular leak in dengue virus infection

GN Malavige, GS Ogg - Immunology, 2017 - Wiley Online Library
Endothelial dysfunction leading to vascular leak is the hallmark of severe dengue. Vascular
leak typically becomes clinically evident 3–6 days after the onset of illness, which is known …

Dengue and COVID-19: two sides of the same coin

GN Malavige, C Jeewandara, GS Ogg - Journal of biomedical science, 2022 - Springer
Abstract Background Many countries in Asia and Latin America are currently facing a double
burden of outbreaks due to dengue and COVID-19. Here we discuss the similarities and …

Platelet activation and apoptosis modulate monocyte inflammatory responses in dengue

ED Hottz, IM Medeiros-de-Moraes… - The Journal of …, 2014 - journals.aai.org
EDH and IMM-d.-M. performed the majority of experiments, analyzed data, and drafted and
prepared the manuscript. EFdA performed some of the experiments and analyzed data. RV …

Interleukin‐17—A multifaceted cytokine in viral infections

U Sahu, D Biswas, VK Prajapati… - Journal of Cellular …, 2021 - Wiley Online Library
Viral infections are a major threat to the human population due to the lack of selective
therapeutic measures. The morbidity and mortality reported worldwide are very alarming …

Changing epidemiology of dengue in Sri Lanka—challenges for the future

GN Malavige, C Jeewandara, A Ghouse… - PLoS neglected …, 2021 - journals.plos.org
Background Dengue infections are on the rise in Sri Lanka and are spreading to all areas in
the country. Here, we discuss the changes in dengue epidemiology in Sri Lanka in relation …

Dengue NS1 antigen as a marker of severe clinical disease

SA Paranavitane, L Gomes, A Kamaladasa… - BMC infectious …, 2014 - Springer
Background Early detection of complications significantly reduces dengue associated
mortality and morbidity. We set out to determine if the NS1 rapid antigen detection test could …