Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#
Abstract Purpose This Position Paper aims to review and discuss the available data on
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …
therapeutic drug monitoring (TDM) of antibacterials, antifungals and antivirals in critically ill …
[HTML][HTML] Model-informed precision dosing: State of the art and future perspectives
IK Minichmayr, E Dreesen, M Centanni, Z Wang… - Advanced drug delivery …, 2024 - Elsevier
Abstract Model-informed precision dosing (MIPD) stands as a significant development in
personalized medicine to tailor drug dosing to individual patient characteristics. MIPD moves …
personalized medicine to tailor drug dosing to individual patient characteristics. MIPD moves …
[HTML][HTML] Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline
AJ Ullmann, JM Aguado, S Arikan-Akdagli… - Clinical Microbiology …, 2018 - Elsevier
Abstract The European Society for Clinical Microbiology and Infectious Diseases, the
European Confederation of Medical Mycology and the European Respiratory Society Joint …
European Confederation of Medical Mycology and the European Respiratory Society Joint …
Utility of voriconazole therapeutic drug monitoring: a meta-analysis
ML Luong, M Al-Dabbagh, AH Groll… - Journal of …, 2016 - academic.oup.com
Background Voriconazole therapeutic drug monitoring (TDM) is increasingly used in clinical
practice. However, the utility of voriconazole TDM to guide therapy remains uncertain and …
practice. However, the utility of voriconazole TDM to guide therapy remains uncertain and …
Trough concentration of voriconazole and its relationship with efficacy and safety: a systematic review and meta-analysis
H Jin, T Wang, BA Falcione, KM Olsen… - Journal of …, 2016 - academic.oup.com
Objectives The optimum trough concentration of voriconazole for clinical response and
safety is controversial. The objective of this review was to determine the optimum trough …
safety is controversial. The objective of this review was to determine the optimum trough …
[HTML][HTML] Clinical practice guideline for the therapeutic drug monitoring of voriconazole in non-Asian and Asian adult patients: consensus review by the Japanese …
Y Takesue, Y Hanai, K Oda, Y Hamada, T Ueda… - Clinical Therapeutics, 2022 - Elsevier
Purpose Voriconazole, an antifungal drug, is metabolized by a cytochrome P450 isozyme.
Increased adverse effects are observed in Asians because of the high rate of poor …
Increased adverse effects are observed in Asians because of the high rate of poor …
CYP2C19 Polymorphisms and Therapeutic Drug Monitoring of Voriconazole: Are We Ready for Clinical Implementation of Pharmacogenomics?
A Owusu Obeng, EF Egelund, A Alsultan… - … : The Journal of …, 2014 - Wiley Online Library
Since its approval by the US Food and Drug Administration in 2002, voriconazole has
become a key component in the successful treatment of many invasive fungal infections …
become a key component in the successful treatment of many invasive fungal infections …
Efficacy and safety of voriconazole and CYP2C19 polymorphism for optimised dosage regimens in patients with invasive fungal infections
T Wang, H Zhu, J Sun, X Cheng, J Xie, H Dong… - International journal of …, 2014 - Elsevier
The aim of this study was to determine an optimum voriconazole target concentration, to
study the influence of CYP2C19 gene status on metabolism of voriconazole and to identify a …
study the influence of CYP2C19 gene status on metabolism of voriconazole and to identify a …
Broad spectrum triazoles for invasive mould infections in adults: Which drug and when?
Invasive mould infections are an increasing cause of morbidity and mortality globally, mainly
due to increasing numbers of immunocompromised individuals at risk for fungal infections …
due to increasing numbers of immunocompromised individuals at risk for fungal infections …
Aspergillus meningitis: a rare clinical manifestation of central nervous system aspergillosis. Case report and review of 92 cases
S Antinori, M Corbellino, L Meroni, F Resta, S Sollima… - Journal of Infection, 2013 - Elsevier
OBJECTIVES: To describe the pathogenesis, clinical presentation, cerebrospinal fluid
findings and outcome of Aspergillus meningitis, meningoencephalitis and arachnoiditis …
findings and outcome of Aspergillus meningitis, meningoencephalitis and arachnoiditis …