Engineering the next generation of cell-based therapeutics
Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …
intractable diseases through uniquely powerful modes of action. Despite notable recent …
Steps in metastasis: an updated review
J Majidpoor, K Mortezaee - Medical Oncology, 2021 - Springer
Metastasis is the most complex and deadly event. Tumor-stromal interface is a place where
invasion of tumor cells in the form of single-cell or collective migration occurs, with the latter …
invasion of tumor cells in the form of single-cell or collective migration occurs, with the latter …
3D bioprinted cancer models: from basic biology to drug development
Effort invested in the development of new drugs often fails to be translated into meaningful
clinical benefits for patients with cancer. The development of more effective anticancer …
clinical benefits for patients with cancer. The development of more effective anticancer …
3D bioprinted multilayered cerebrovascular conduits to study cancer extravasation mechanism related with vascular geometry
Cerebral vessels are composed of highly complex structures that facilitate blood perfusion
necessary for meeting the high energy demands of the brain. Their geometrical complexities …
necessary for meeting the high energy demands of the brain. Their geometrical complexities …
Bioprinting methods for fabricating in vitro tubular blood vessel models
Dysfunctional blood vessels are implicated in various diseases, including cardiovascular
diseases, neurodegenerative diseases, and cancer. Several studies have attempted to …
diseases, neurodegenerative diseases, and cancer. Several studies have attempted to …
Circulating tumor cells: from new biological insights to clinical practice
X Gu, S Wei, X Lv - Signal Transduction and Targeted Therapy, 2024 - nature.com
The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …
tumor cells migrate through the bloodstream from the original site to other parts of the body …
Intelligent vascularized 3D/4D/5D/6D-printed tissue scaffolds
Blood vessels are essential for nutrient and oxygen delivery and waste removal. Scaffold-
repairing materials with functional vascular networks are widely used in bone tissue …
repairing materials with functional vascular networks are widely used in bone tissue …
Clinical applications of patient-specific 3D printed models in cardiovascular disease: current status and future directions
Z Sun - Biomolecules, 2020 - mdpi.com
Three-dimensional (3D) printing has been increasingly used in medicine with applications in
many different fields ranging from orthopaedics and tumours to cardiovascular disease …
many different fields ranging from orthopaedics and tumours to cardiovascular disease …
Adaptable microfluidic vessel-on-a-chip platform for investigating tumor metastatic transport in bloodstream
Cancer metastasis counts for 90% of cancer fatalities, and its development process is still a
mystery. The dynamic process of tumor metastatic transport in the blood vessel is not well …
mystery. The dynamic process of tumor metastatic transport in the blood vessel is not well …
[HTML][HTML] Development and recent advancement in microfluidics for point of care biosensor applications: A review
Capillaries are small microscopic channels found in nature predominantly. These flow blood
in animals and food, water and nutritions in plants. Mimicking these capillaries scientist …
in animals and food, water and nutritions in plants. Mimicking these capillaries scientist …