Bipolar disorders

RS McIntyre, M Berk, E Brietzke, BI Goldstein… - The Lancet, 2020 - thelancet.com
Bipolar disorders are a complex group of severe and chronic disorders that includes bipolar
I disorder, defined by the presence of a syndromal, manic episode, and bipolar II disorder …

Epidemiology and risk factors for bipolar disorder

TA Rowland, S Marwaha - Therapeutic advances in …, 2018 - journals.sagepub.com
Bipolar disorder is a multifactorial illness with uncertain aetiology. Knowledge of potential
risk factors enables clinicians to identify patients who are more likely to develop bipolar …

Environmental noise‐induced effects on stress hormones, oxidative stress, and vascular dysfunction: Key factors in the relationship between cerebrocardiovascular …

O Hahad, JH Prochaska, A Daiber… - Oxidative medicine and …, 2019 - Wiley Online Library
The role of noise as an environmental pollutant and its adverse effects on health are being
increasingly recognized. Beyond its direct effects on the auditory system (eg, hearing loss …

[HTML][HTML] Associations of immunological proteins/traits with schizophrenia, major depression and bipolar disorder: A bi-directional two-sample mendelian …

BI Perry, R Upthegrove, N Kappelmann… - Brain, behavior, and …, 2021 - Elsevier
Background Schizophrenia, bipolar disorder and depression are associated with
inflammation. However, it is unclear whether associations of immunological proteins/traits …

[HTML][HTML] Inflammation, anxiety, and stress in bipolar disorder and borderline personality disorder: A narrative review

LF Saccaro, Z Schilliger, A Dayer, N Perroud… - Neuroscience & …, 2021 - Elsevier
Bipolar disorder (BD) and borderline personality disorder (BPD) are serious and prevalent
psychiatric diseases that share common phenomenological characteristics: symptoms (such …

Inflammatory signaling mechanisms in bipolar disorder

GH Jones, CM Vecera, OF Pinjari… - Journal of Biomedical …, 2021 - Springer
Bipolar disorder is a decidedly heterogeneous and multifactorial disease, with a high
individual and societal burden. While not all patients display overt markers of elevated …

The immune profile of major dysmood disorder: proof of concept and mechanism using the precision nomothetic psychiatry approach

M Maes, M Rachayon, K Jirakran, P Sodsai… - Cells, 2022 - mdpi.com
Major depressive disorder and a major depressive episode (MDD/MDE) are characterized
by activation of the immune-inflammatory response system (IRS) and the compensatory …

Oxidative stress parameters and antioxidants in patients with bipolar disorder: Results from a meta‐analysis comparing patients, including stratification by polarity and …

S Jiménez‐Fernández, M Gurpegui… - Bipolar …, 2021 - Wiley Online Library
Objective To investigate oxidative stress markers and antioxidants in bipolar disorder (BD).
Methods Electronic MEDLINE/PubMed/Cochrane‐Library/Scopus/TripDatabase search until …

A peripheral inflammatory signature discriminates bipolar from unipolar depression: a machine learning approach

S Poletti, B Vai, MG Mazza, R Zanardi, C Lorenzi… - Progress in Neuro …, 2021 - Elsevier
Background Mood disorders (major depressive disorder, MDD, and bipolar disorder, BD)
are considered leading causes of life-long disability worldwide, where high rates of no …

Shared pathways for neuroprogression and somatoprogression in neuropsychiatric disorders

G Morris, BK Puri, AJ Walker, M Maes… - Neuroscience & …, 2019 - Elsevier
Activated immune-inflammatory, oxidative and nitrosative stress (IO&NS) pathways and
consequent mitochondrial aberrations are involved in the pathophysiology of psychiatric …