Small ruminants and its use in regenerative medicine: Recent works and future perspectives

RD Alvites, MV Branquinho, AC Sousa, B Lopes… - Biology, 2021 - mdpi.com
Simple Summary Small ruminants such as sheep and goats have been increasingly used as
animal models due to their dimensions, physiology and anatomy identical to those of …

Mesenchymal stem cell studies in the goat model for biomedical research—A review of the scientific literature

IE Dias, CA Viegas, JF Requicha, MJ Saavedra… - Biology, 2022 - mdpi.com
Simple Summary This review article aims to compile the works published in the scientific
literature, over the last two decades, that use the goat as an animal model in preclinical …

Current practice in animal models for pelvic floor dysfunction

F Fang, Z Zhao, J Xiao, J Wen, J Wu, Y Miao - International Urogynecology …, 2023 - Springer
Introduction and hypothesis The objective was to explore the current practice of using
animal models for female pelvic floor dysfunction (PFD). Methods By applying PFD and …

Dog Mesenchymal Stem Cell Basic Research and Potential Applications

MB Gugjoo, A Pal, GT Sharma - Mesenchymal Stem Cell in Veterinary …, 2020 - Springer
Mesenchymal stem cells (MSCs) being available in numerous adult tissues and foetal
membranes have been harvested from almost all these sources in dog. Due to the presence …

Ibuprofen in therapeutic concentrations affects the secretion of human bone marrow mesenchymal stromal cells, but not their proliferative and migratory capacity

A Kulesza, K Zielniok, J Hawryluk, L Paczek… - Biomolecules, 2022 - mdpi.com
Mesenchymal stromal cells (MSCs) are able to modulate the immune system activity and the
regeneration processes mainly through the secretion of multiple soluble factors, including …

Intraurethral co-transplantation of bone marrow mesenchymal stem cells and muscle-derived cells improves the urethral closure

A Burdzinska, B Dybowski… - Stem Cell Research & …, 2018 - Springer
Background Cell therapy constitutes an attractive alternative to treat stress urinary
incontinence. Although promising results have been demonstrated in this field, the …

The influence of cell source and donor age on the tenogenic potential and chemokine secretion of human mesenchymal stromal cells

W Zarychta-Wiśniewska, A Burdzińska… - Stem Cells …, 2019 - Wiley Online Library
Background. Cellular therapy is proposed for tendinopathy treatment. Bone marrow‐(BM‐
MSC) and adipose tissue‐(ASC) derived mesenchymal stromal cells are candidate …

In vivo imaging system for explants analysis—A new approach for assessment of cell transplantation effects in large animal models

W Zarychta-Wiśniewska, A Burdzinska, R Zagozdzon… - PloS one, 2017 - journals.plos.org
Introduction Despite spectacular progress in cellular transplantology, there are still many
concerns about the fate of transplanted cells. More preclinical studies are needed …

Vadadustat, a HIF prolyl hydroxylase inhibitor, improves immunomodulatory properties of human mesenchymal stromal cells

K Zielniok, A Burdzinska, B Kaleta, R Zagozdzon… - Cells, 2020 - mdpi.com
The therapeutic potential of mesenchymal stromal cells (MSCs) is largely attributed to their
immunomodulatory properties, which can be further improved by hypoxia priming. In this …

Limited accuracy of transurethral and periurethral intrasphincteric injections of cellular suspension

A Burdzinska, B Dybowski… - Neurourology and …, 2018 - Wiley Online Library
Aims The efficacy of cell therapy in patients with stress urinary incontinence (SUI) is lower
than expected. The aim of this study was to determine the injection accuracy rate both with …