Electroporation designates the use of short high‐voltage pulses to overcome the barrier of
the cell membrane. By applying an external electric field, which just surpasses the …

The success of gene therapy is largely dependent on the development of the gene delivery
vector. Recently, gene transfection into target cells using naked DNA, which is a simple and …

Nondestructive, high‐efficiency, and on‐demand intracellular drug/biomacromolecule
delivery for therapeutic purposes remains a great challenge. Herein, a biomechanical …

This study introduces a new method for minimally invasive treatment of cancer—the ablation
of undesirable tissue through the use of irreversible electroporation. Electroporation is the …

Electroporation by using pulsed electric fields with long durations compared with the
charging time of the plasma membrane can induce cell fusion or introduce xenomolecules …

In order to enhance and target gene delivery we have previously established a novel
method, termed magnetofection, which uses magnetic force acting on gene vectors that are …

While initial approaches to adoptive T cell therapy relied on the identification and expansion
of rare tumour-reactive T cells, genetic engineering has transformed cancer immunotherapy …

Development of an efficient method for introducing a therapeutic gene into target cells in
vivo is the key issue in treating genetic and acquired diseases by gene therapy. To this end …

Materials play a key role in several biomedical applications, and it is imperative that both the
materials and biological aspects are clearly understood for attaining a successful biological …

Increases in efficiency have made naked DNA gene transfer a viable method for gene
therapy. Intravascular delivery results in effective gene delivery to liver and muscle, and …