Comparative efficacy and tolerability of 32 oral and long-acting injectable antipsychotics for the maintenance treatment of adults with schizophrenia: a systematic …
J Schneider-Thoma, K Chalkou, C Dörries, I Bighelli… - The lancet, 2022 - thelancet.com
Background Schizophrenia is a common, severe, and usually chronic disorder. Maintenance
treatment with antipsychotic drugs can prevent relapse but also causes side-effects. We …
treatment with antipsychotic drugs can prevent relapse but also causes side-effects. We …
Improving outcomes of first‐episode psychosis: an overview
P Fusar‐Poli, PD McGorry, JM Kane - World psychiatry, 2017 - Wiley Online Library
Outcomes of psychotic disorders are associated with high personal, familiar, societal and
clinical burden. There is thus an urgent clinical and societal need for improving those …
clinical burden. There is thus an urgent clinical and societal need for improving those …
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …
Remission and recovery from first-episode psychosis in adults: systematic review and meta-analysis of long-term outcome studies
BackgroundRemission and recovery rates for people with first-episode psychosis (FEP)
remain uncertain. AimsTo assess pooled prevalence rates of remission and recovery in FEP …
remain uncertain. AimsTo assess pooled prevalence rates of remission and recovery in FEP …
Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors
BackgroundWe examined longitudinally the course and predictors of treatment resistance in
a large cohort of first-episode psychosis (FEP) patients from initiation of antipsychotic …
a large cohort of first-episode psychosis (FEP) patients from initiation of antipsychotic …
Psychosis
DB Arciniegas - CONTINUUM: lifelong learning in neurology, 2015 - journals.lww.com
Abstract Purpose of Review: Psychosis is a common and functionally disruptive symptom of
many psychiatric, neurodevelopmental, neurologic, and medical conditions and an …
many psychiatric, neurodevelopmental, neurologic, and medical conditions and an …
Two distinct patterns of treatment resistance: clinical predictors of treatment resistance in first-episode schizophrenia spectrum psychoses
BackgroundClozapine remains the only evidence-based antipsychotic for treatment-
resistant schizophrenia (TRS). The ability to predict which patients with their first onset of …
resistant schizophrenia (TRS). The ability to predict which patients with their first onset of …
Should psychiatrists be more cautious about the long-term prophylactic use of antipsychotics?
Patients who recover from an acute episode of psychosis are frequently prescribed
prophylactic antipsychotics for many years, especially if they are diagnosed as having …
prophylactic antipsychotics for many years, especially if they are diagnosed as having …
Cognitive change in schizophrenia and other psychoses in the decade following the first episode
Objective: Schizophrenia is associated with a marked cognitive impairment that is widely
believed to remain stable after illness onset. Yet, to date, 10-year prospective studies of …
believed to remain stable after illness onset. Yet, to date, 10-year prospective studies of …
Stress sensitivity, aberrant salience, and threat anticipation in early psychosis: an experience sampling study
While contemporary models of psychosis have proposed a number of putative psychological
mechanisms, how these impact on individuals to increase intensity of psychotic experiences …
mechanisms, how these impact on individuals to increase intensity of psychotic experiences …