HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management

M Lechner, J Liu, L Masterson, TR Fenton - Nature reviews Clinical …, 2022 - nature.com
Abstract Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high …

Consensuses, controversies, and future directions in treatment deintensification for human papillomavirus‐associated oropharyngeal cancer

JJ Kang, Y Yu, L Chen, K Zakeri… - CA: a cancer journal …, 2023 - Wiley Online Library
The most common cancer caused by human papillomavirus (HPV) infection in the United
States is oropharyngeal cancer (OPC), and its incidence has been rising since the turn of the …

[HTML][HTML] De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma: a systematic review and meta-analysis of …

L Masterson, D Moualed, ZW Liu, JEF Howard… - European journal of …, 2014 - Elsevier
Iatrogenic complications associated with current treatment protocols for oropharyngeal
squamous cell carcinoma are noted to cause high rates of acute and chronic morbidity. The …

HPV detection in head and neck squamous cell carcinomas: what is the issue?

JG Augustin, C Lepine, A Morini, A Brunet… - Frontiers in …, 2020 - frontiersin.org
Besides classic tobacco and alcohol risk factors, human papillomavirus (HPV) plays a role in
the development of a subset of head and neck squamous cell carcinomas (HNSCCs), and …

Update from the 5th edition of the World Health Organization classification of head and neck tumors: oropharynx and nasopharynx

C Badoual - Head and neck pathology, 2022 - Springer
The new WHO classification of head and neck tumors provides a comprehensive overview
of lesions by summarizing their clinical, epidemiological, histological, immunohistochemical …

[HTML][HTML] Structural and enzyme kinetic studies of retrograded starch: Inhibition of α-amylase and consequences for intestinal digestion of starch

H Patel, PG Royall, S Gaisford, GR Williams… - Carbohydrate …, 2017 - Elsevier
Retrograded starch is known to be resistant to digestion. We used enzyme kinetic
experiments to examine how retrogradation of starch affects amylolysis catalysed by porcine …

Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach

SG Craig, LA Anderson, AG Schache, M Moran… - British Journal of …, 2019 - nature.com
Background TNM8 staging for oropharyngeal squamous cell carcinomas (OPSCC)
surrogates p16 immunohistochemistry for HPV testing. Patients with p16+ OPSCC may lack …

Current role of surgery in the management of oropharyngeal cancer

W Golusiński, E Golusińska-Kardach - Frontiers in oncology, 2019 - frontiersin.org
In the last few decades, the surgical treatment of oropharyngeal squamous cell carcinoma
(OPSCC) has undergone enormous changes. Until the 1990s, open surgery was the primary …

Current role of primary surgical treatment in patients with head and neck squamous cell carcinoma

A Bozec, D Culié, G Poissonnet… - Current opinion in …, 2019 - journals.lww.com
Surgery should be the primary treatment modality for most resectable oral cavity cancers
and for T4a laryngeal/hypopharyngeal cancers. Primary surgery could also be the preferred …

Human papilloma virus: an unraveled enigma of universal burden of malignancies

I Khan, R Harshithkumar, A More, A Mukherjee - Pathogens, 2023 - mdpi.com
HPV, or Human Papilloma Virus, has been the primary causative agent of genital warts and
cervical cancer worldwide. It is a sexually transmitted infection mainly affecting women of …