Sites which bind oxytocin and vasopressin with high affinity were detected in the brain and
upper spinal cord of 12 human subjects, using in vitro light microscopic autoradiography …

Preterm birth (before 37 completed weeks of gestation) continues to account for the vast
majority of neonatal morbidity and mortality. The incidence of preterm birth can be reduced …

Tocolytic agents are drugs designed to inhibit contractions of myometrial smooth muscle
cells. Such an effect has been demonstrated in vitro or in vivo for several pharmacological …

Abstract Oxytocin (OT) receptor (OTR) concentrations were determined in the cervix of
nonpregnant cows on cycle Days 0, 3, 7–8, 17, and 19 (n= 3− 4 cows each day);[3H] OT was …

In the present study, we investigated the possible mechanisms by which oxytocin might
regulate oxytocin receptor (OTR) density. Exposure of cultured myometrial cells to oxytocin …

Objective: To review the potential roles of oxytocin (OT) and its receptor (OTR) in the
regulation of parturition. Methods: We reviewed the literature to describe thhe molecular …

Pregnancy and early life create specific psychosomatic challenges for the mother and child,
such as changes in hemodynamics, resetting of the water-electrolyte balance, hypoxia, pain …

The binding of [3H] oxytocin ([3H]-0T) and [3H] arginine vasopressin ([3H]-AVP) by bovine
endometrial and myometrial membrane preparations obtained on days 0, 7, 14, 17, and 21 …

OBJECTIVE: The objective of the study was to compare barusiban with placebo in
threatened preterm labor. STUDY DESIGN: This was a randomized, double-blind, placebo …

V irtually all hormones, neurohormones, neurotransmitters, neuropeptides, drugs, and other
ligands initiate their biological effects by binding to specific receptors. Myometrial function is …