This review is focused on purinergic neurotransmission, ie, ATP released from nerves as a
transmitter or cotransmitter to act as an extracellular signaling molecule on both pre-and …

The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

In 1929 Drury and Szent-Györgyi published a seminal paper describing the potent actions of
adenine compounds. Some decades later, adenosine 5'-triphosphate (ATP) was proposed …

Loss of olfactory function has been commonly reported in SARS-CoV-2 infections. Recovery
from anosmia is not well understood. Previous studies showed that sustentacular cells, and …

All cells release nucleotides and are in one way or another involved in local autocrine and
paracrine regulation of organ function via stimulation of purinergic receptors. Significant …

Treating pain by inhibiting ATP activation of P2X3-containing receptors heralds an exciting
new approach to pain management, and Afferent's program marks the vanguard in a new …

Following hints in the early literature about adenosine 5′-triphosphate (ATP) injections
producing pain, an ion-channel nucleotide receptor was cloned in 1995, P2X3 subtype …

There is a brief summary of the early background literature about purinergic signalling and
its involvement in pain, of ATP storage, release and ectoenzymatic breakdown and of the …

We consider the impact of purinergic signaling on the physiology of the special senses of
vision, smell, taste and hearing. Purines (particularly ATP and adenosine) act as …

We investigated the cellular mechanism underlying presynaptic regulation of olfactory
receptor neuron (ORN) input to the mouse olfactory bulb using optical-imaging techniques …