Molecular mechanisms in thioacetamide-induced acute and chronic liver injury models
D Ezhilarasan - Environmental Toxicology and Pharmacology, 2023 - Elsevier
Thioacetamide (TAA) undergoes bioactivation in the liver by the CYP450 2E1 enzyme,
resulting in the formation of TAA-S-oxide and TAA-S-dioxide. TAA-S-dioxide induces …
resulting in the formation of TAA-S-oxide and TAA-S-dioxide. TAA-S-dioxide induces …
[HTML][HTML] Ginsenoside Rg1 alleviates ANIT-induced cholestatic liver injury by inhibiting hepatic inflammation and oxidative stress via SIRT1 activation
Q Gao, G Li, Y Zu, Y Xu, C Wang, D Xiang, W He… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Ginseng (Panax ginseng CA Mey) is a common
traditional Chinese medicine used for anti-inflammation, treating colitis, type 2 diabetes …
traditional Chinese medicine used for anti-inflammation, treating colitis, type 2 diabetes …
[HTML][HTML] The beneficial potential of ginseng for menopause
JH Song, N Lee, HJ Yang, MS Lee, SR Kopalli… - Journal of Ginseng …, 2024 - Elsevier
Abstract Korean Red Ginseng (KRG) has long been used not only as a food supplement but
also as a treatment for various diseases. Ginseng originated in South Korea, which later …
also as a treatment for various diseases. Ginseng originated in South Korea, which later …
Eplerenone modulates the inflammatory response in monosodium iodoacetate-induced knee osteoarthritis in rats: involvement of RANKL/OPG axis
RE Mostafa, AAA Salama - Life Sciences, 2023 - Elsevier
Aims Osteoarthritis (OA) is a multifactorial degenerative disease marked by the progressive
deterioration of articular cartilage with inflammation of the synovium. OA's main symptoms …
deterioration of articular cartilage with inflammation of the synovium. OA's main symptoms …
Panax ginseng ameliorates hepatorenal oxidative alterations induced by commercially used cypermethrin in male rats: experimental and molecular docking …
Cypermethrin (CYP) is a synthetic pyrethroid utilized as an insecticide in agriculture and
various pest eradication programs. However, it induces numerous health hazards for …
various pest eradication programs. However, it induces numerous health hazards for …
Hepatoprotective potential of a novel quinazoline derivative in thioacetamide-induced liver toxicity
S Salama, CS Kue, H Mohamad, F Omer… - Frontiers in …, 2022 - frontiersin.org
Purpose: The compound quinazoline Q-Br, 3-(5-bromo-2-hydroxybenzylideneamino)-2-(5-
bromo-2 hydroxyphenyl) 2, 3-dihydroquinazoline-4 (1H)-one (Q-Br) was evaluated for its …
bromo-2 hydroxyphenyl) 2, 3-dihydroquinazoline-4 (1H)-one (Q-Br) was evaluated for its …
Ginseng® Alleviates Malathion-Induced Hepatorenal Injury through Modulation of the Biochemical, Antioxidant, Anti-Apoptotic, and Anti-Inflammatory Markers in Male …
This study aims to see if Ginseng® can reduce the hepatorenal damage caused by
malathion. Four groups of forty male Wistar albino rats were alienated. Group 1 was a …
malathion. Four groups of forty male Wistar albino rats were alienated. Group 1 was a …
Screening of Potential α-Glucosidase Inhibitors from the Roots and Rhizomes of Panax Ginseng by Affinity Ultrafiltration Screening Coupled with UPLC-ESI-Orbitrap …
HP Wang, CL Fan, ZZ Lin, Q Yin, C Zhao, P Peng… - Molecules, 2023 - mdpi.com
Panax ginseng was a traditional Chinese medicine with various pharmacological activities
and one of its important activities was hypoglycemic activity; therefore, panax ginseng has …
and one of its important activities was hypoglycemic activity; therefore, panax ginseng has …
Protective effects of royal jelly and Echinacea against moxifloxacin-induced renal and hepatic injury in rats
RE Mostafa, NM Shaffie, RM Allam - Drug and Chemical …, 2023 - Taylor & Francis
Antibiotic use, especially fluoroquinolones, has been linked to extensive renal and hepatic
injury thus inflicts a considerable health problem. Fifty rats were allocated into five groups …
injury thus inflicts a considerable health problem. Fifty rats were allocated into five groups …
[PDF][PDF] Analysis of ginseng in the treatment of Interstitial Cystitis/Bladder Pain Syndrome based on network pharmacology.
L Wang, L Yuan - European Review for Medical & …, 2022 - europeanreview.org
OBJECTIVE: The network pharmacology is adopted in the paper to elaborate the active
components, targets, and pathways of ginseng in the treatment of Interstitial Cystitis/Bladder …
components, targets, and pathways of ginseng in the treatment of Interstitial Cystitis/Bladder …