Cutaneous wound healing consists of three main phases: inflammation, re-epithelialization,
and tissue remodeling. During normal wound healing, these processes are tightly regulated …

Hypertrophic scars (HS) and keloids (KD) are lesions that develop as a result of excessive
fibroblast proliferation and collagen deposition in response to dermal injury, leading to …

Background Marfan syndrome (MFS) is a genetic disorder caused by mutations in fibrillin-1
and is characterized by thoracic aortic aneurysms and other complications. Previous studies …

Cellular therapies play an important role in tendon tissue engineering, with tenocytes being
the most prominent and potent cell population available. However, for the development of a …

Extensive scar tissue formation often occurs after severe burn injury, trauma, or as one of
complications after surgical intervention. Despite significant therapeutic advances, it is still a …

Background The pathology of keloid and especially the roles of bacteria on it were not well
understood. Methods In this study, multi-omics analyses including microbiome …

Background Keloids represent benign fibroproliferative tumors which result from elevated
expression of inflammation. Paclitaxel (PTX) was an effective chemotherapeutic agent and …

Scars are composed of stiff collagen fibers, which contract strongly owing to the action of
myofibroblasts. To explore the substances that modulate scar contracture, the fibroblast …

Burns account for more than 265,000 deaths per year in the world, mainly associated with
infections. Therefore, the shorter the healing time, the better the prognosis. Based on this …

Introduction Keloids are excessive fibroproliferative diseases that are caused by abnormal
wound healing. The anti-proliferative activity of Physalis angulata compounds has potential …