This review describes the progress that has been achieved since adaptive optics (AO) was
incorporated into the ophthalmoscope a quarter of a century ago, transforming our ability to …

Adaptive optics scanning light ophthalmoscopy (AOSLO) allows visualization of the living
human retina with exquisite single-cell resolution. This technology has improved our …

Stem cell-based transplantation therapies offer hope for currently untreatable retinal
degenerations; however, preclinical progress has been largely confined to rodent models …

All retina-based vision restoration approaches rely on the assumption that photoreceptor
loss does not preclude reactivation of the remaining retinal architecture. Whether extended …

Rod and cone photoreceptors degenerate in retinitis pigmentosa and age-related macular
degeneration, robbing the visual system of light-triggered signals necessary for sight …

With electrical stimulation, retinal prostheses bypass dysfunctional photoreceptors and
activate the surviving bipolar or retinal ganglion cells (RGCs). Therefore, the effective …

The anatomical differences between the retinas of humans and most animal models pose a
challenge for testing novel therapies. Nonhuman primate (NHP) retina is anatomically …

Inherited retinal diseases (IRDs) represent a genetically and clinically heterogenous group
of diseases that can eventually lead to blindness. Advances in sequencing technologies …

Case Report: Multimodal, Longitudinal Assessment of Retinal... : Optometry and Vision
Science Case Report: Multimodal, Longitudinal Assessment of Retinal Structure and Function …

In response to central nervous system (CNS) injury, tissue resident immune cells such as
microglia and circulating systemic neutrophils are often first responders. The degree to …