Harnessing the potential of probiotics in the treatment of alcoholic liver disorders

G Mishra, P Singh, M Molla, YS Yimer… - Frontiers in …, 2023 - frontiersin.org
In the current scenario, prolonged consumption of alcohol across the globe is upsurging an
appreciable number of patients with the risk of alcohol-associated liver diseases. According …

Clinical efficacy of probiotics in the treatment of alcoholic liver disease: a systematic review and meta-analysis

SY Xiong, GS Wu, C Li, W Ma, HR Luo - Frontiers in Cellular and …, 2024 - frontiersin.org
Objective Alcoholic liver disease (ALD) is a liver damage disease caused by long-term
heavy drinking. Currently, there is no targeted pharmaceutical intervention available for the …

1-O-Actylbritannilactone Ameliorates Alcohol-Induced Hepatotoxicity through Regulation of ROS/Akt/NF-κB-Mediated Apoptosis and Inflammation

L Xie, Z Yang, Y Wang, J Hu, Y Lu, H Zhang, S Jiang… - ACS …, 2022 - ACS Publications
1-O-Acetylbritannilactone (ABL) is a marker component of Inula britannica L. and is reported
to exhibit multiple pharmacological activities, including antiaging, anti-inflammatory, and …

Exploring the therapeutic potential of garlic in alcoholic liver disease: a network pharmacology and experimental validation study

S Gao, T Gao, L Li, S Wang, J Hu, R Zhang, Y Zhou… - Genes & Nutrition, 2024 - Springer
Objective Employing network pharmacology and molecular docking, the study predicts the
active compounds in garlic and elucidates their mechanism in inhibiting the development of …

Alcohol-related liver disease including new developments

PV Patel, SL Flamm - Clinics in Liver Disease, 2023 - liver.theclinics.com
The rate of alcohol consumption and prevalence of alcohol use disorder (AUD) is on the
rise. In fact, 1 in 12 adults in the United States report heavy alcohol consumption, which is …

Coronavirus disease-2019 and implications on the liver

PT Campbell, OK Fix - Clinics in Liver Disease, 2022 - pmc.ncbi.nlm.nih.gov
The coronavirus disease-2019 (COVID-19) pandemic has had a large impact on patients
with chronic liver disease (CLD) and liver transplantation (LT) recipients. Patients with …

[HTML][HTML] Screening, diagnosis, and treatment of alcohol-related liver disease and alcohol-associated hepatitis

PV Patel, SL Flamm - Gastroenterology & Hepatology, 2022 - ncbi.nlm.nih.gov
Alcohol-related liver disease is a spectrum of disease in which continued, significant alcohol
use can cause progression from fatty changes in the liver to inflammation, fibrosis, and …

[HTML][HTML] Acetylation of proximal cysteine-lysine pairs by alcohol metabolism

CD McGinnis, PS Harris, BIM Graham, JO Marentette… - Redox Biology, 2025 - Elsevier
Alcohol consumption induces hepatocyte damage through complex processes involving
oxidative stress and disrupted metabolism. These factors alter proteomic and epigenetic …

Peroxisome proliferator-activated receptor agonists: A new hope towards the management of alcoholic liver disease

SSK Durairajan, AK Singh… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
In this editorial, we examine a paper by Koizumi et al, on the role of peroxisome proliferator-
activated receptor (PPAR) agonists in alcoholic liver disease (ALD). The study determined …

Using phosphatidylethanol as an adjunct to self-reported alcohol use improves identification of liver fibrosis risk

PM Murnane, M Afshar, G Chamie… - Official journal of the …, 2022 - journals.lww.com
Methods: We pooled individual-level data from 12 studies from the United States, Russia,
Uganda, and South Africa with PEth, AUDIT-C (Alcohol Use Disorders Identification Test …