Opioid analgesics are recognized as a legitimate medical therapy for selected patients with
severe chronic pain that does not respond to other therapies. However, opioids are …

Understanding Links among Opioid Use, Overdose, and Suicide | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

In recent years, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for
Adult Cancer Pain have undergone substantial revisions focusing on the appropriate and …

Importance Successful treatment of opioid misuse among people with chronic pain has
proven elusive. Guidelines recommend nonopioid therapies, but the efficacy of mindfulness …

Use of chronic opioid therapy for chronic noncancer pain has increased substantially. The
American Pain Society and the American Academy of Pain Medicine commissioned a …

Objective: Opioid pharmacotherapy is now the leading treatment for chronic pain, a problem
that affects nearly one third of the US population. Given the dramatic rise in prescription …

Pain is a complex phenomenon caused by noxious sensory stimuli or neuropathological
mechanisms. An individual's memories, expectations, and emotions modify the experience …

Background: Deaths due to prescription opioid overdoses have increased dramatically. High-
quality guidelines could help clinicians mitigate risks associated with opioid therapy …

Purpose To provide evidence-based guidance on the optimum management of chronic pain
in adult cancer survivors. Methods An ASCO-convened expert panel conducted a systematic …

Background: To ensure seriously ill people and their families receive high-quality primary
and specialty palliative care services, rigorous methods are needed to prospectively identify …