The oralome is the summary of the dynamic interactions orchestrated between the
ecological community of oral microorganisms (comprised of up to approximately 1000 …

The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …

The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …

Ferumoxytol is an intravenous iron oxide nanoparticle formulation that has been approved
by the US Food and Drug Administration (FDA) for treating anemia in patients with chronic …

Bacterial-infections are mostly due to bacteria in an adhering, biofilm-mode of growth and
not due to planktonically growing, suspended-bacteria. Biofilm-bacteria are much more …

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause
chronic infections. The multifactorial nature of biofilm development and drug tolerance …

Enamel, once formed, loses the ability to regenerate due to the loss of the formative
ameloblasts. It is subjected to constant damaging events due to exposure to external agents …

Biofilms are microbial communities embedded within an extracellular matrix, forming a
highly organized structure that causes many human infections. Dental caries (tooth decay) is …

Smart biomaterials can sense and react to physiological or external environmental stimuli
(eg, mechanical, chemical, electrical, or magnetic signals). The last decades have seen …

The increasing resistance of bacteria to existing antibiotics constitutes a major public health
threat globally. Most current antibiotic treatments are hindered by poor delivery to the …