Uncovering sex differences of rodent microglia

J Han, Y Fan, K Zhou, K Blomgren… - Journal of …, 2021 - Springer
There are inherent structural and functional differences in the central nervous systems
(CNS) of females and males. It has been gradually established that these sex-specific …

Cholinergic modulation of glial function during aging and chronic neuroinflammation

R Gamage, I Wagnon, I Rossetti, R Childs… - Frontiers in Cellular …, 2020 - frontiersin.org
Aging is a complex biological process that increases the risk of age-related cognitive
degenerative diseases such as dementia, including Alzheimer's disease (AD), Lewy Body …

Adverse childhood experiences predict the phenome of affective disorders and these effects are mediated by staging, neuroimmunotoxic and growth factor profiles

M Maes, M Rachayon, K Jirakran, P Sodsai… - Cells, 2022 - mdpi.com
Adverse childhood experiences (ACEs) enhance pro-inflammatory and pro-oxidant
responses. In affective disorders, recent precision nomothetic psychiatry studies disclosed …

Healthy lifestyles and wellbeing reduce neuroinflammation and prevent neurodegenerative and psychiatric disorders

E Kip, LC Parr-Brownlie - Frontiers in Neuroscience, 2023 - frontiersin.org
Since the mid-20th century, Western societies have considered productivity and economic
outcomes are more important than focusing on people's health and wellbeing. This focus …

Stress, depression, and risk of dementia–a cohort study in the total population between 18 and 65 years old in Region Stockholm

J Wallensten, G Ljunggren, A Nager, C Wachtler… - Alzheimer's Research & …, 2023 - Springer
Background Chronic stress and depression are potential risk factors for mild cognitive
impairment and dementia, including Alzheimer disease. The aim was to investigate whether …

Polyploidy as a fundamental phenomenon in evolution, development, adaptation and diseases

OV Anatskaya, AE Vinogradov - International Journal of Molecular …, 2022 - mdpi.com
DNA replication during cell proliferation is 'vertical'copying, which reproduces an initial
amount of genetic information. Polyploidy, which results from whole-genome duplication, is …

[HTML][HTML] The gut-brain connection: Exploring the influence of the gut microbiota on neuroplasticity and neurodevelopmental disorders

F Damiani, S Cornuti, P Tognini - Neuropharmacology, 2023 - Elsevier
Neuroplasticity refers to the ability of brain circuits to reorganize and change the properties
of the network, resulting in alterations in brain function and behavior. It is traditionally …

PARK7/DJ-1 in microglia: implications in Parkinson's disease and relevance as a therapeutic target

F Lind-Holm Mogensen, A Scafidi, A Poli… - Journal of …, 2023 - Springer
Microglia are the immune effector cells of the brain playing critical roles in immune
surveillance and neuroprotection in healthy conditions, while they can sustain …

Microglia-mediated neurodegeneration in perinatal brain injuries

B Fleiss, J Van Steenwinckel, C Bokobza, I K. Shearer… - Biomolecules, 2021 - mdpi.com
Perinatal brain injuries, including encephalopathy related to fetal growth restriction,
encephalopathy of prematurity, neonatal encephalopathy of the term neonate, and neonatal …

Early life stress detection using physiological signals and machine learning pipelines

Z Shahbazi, YC Byun - Biology, 2023 - mdpi.com
Simple Summary Problem statement: Stress is one of the challenges of human life that in
case of not curing may cause serious problems in human body. There are various type of …