Endoplasmic reticulum chaperones in viral infection: therapeutic perspectives

E Kohli, S Causse, V Baverel, L Dubrez… - Microbiology and …, 2021 - Am Soc Microbiol
Viruses are intracellular parasites that subvert the functions of their host cells to accomplish
their infection cycle. The endoplasmic reticulum (ER)-residing chaperone proteins are …

Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: multicentric Castleman disease (KSHV–MCD) and the KSHV inflammatory cytokine syndrome

MN Polizzotto, TS Uldrick, D Hu… - Frontiers in microbiology, 2012 - frontiersin.org
Soon after the discovery of Kaposi sarcoma (KS)-associated herpesvirus (KSHV), it was
appreciated that this virus was associated with most cases of multicentric Castleman …

KSHV: pathways to tumorigenesis and persistent infection

L Giffin, B Damania - Advances in virus research, 2014 - Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8) is
the etiologic agent of Kaposi's sarcoma, primary effusion lymphoma, and multicentric …

The role of Kaposi sarcoma‐associated herpesvirus in the pathogenesis of Kaposi sarcoma

S Gramolelli, TF Schulz - The Journal of pathology, 2015 - Wiley Online Library
Kaposi sarcoma (KS) is an unusual vascular tumour caused by an oncogenic‐herpesvirus,
Kaposi sarcoma‐associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV …

Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins

AM Cheatham, NR Sharma… - Journal of Cell Biology, 2023 - rupress.org
In mammalian cells, misfolded glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-
APs) are cleared out of the ER to the Golgi via a constitutive and a stress-inducible pathway …

Viral interleukin-6: role in Kaposi's sarcoma-associated herpesvirus–associated malignancies

S Sakakibara, G Tosato - Journal of Interferon & Cytokine Research, 2011 - liebertpub.com
Viral interleukin-6 (vIL-6) is a product of Kaposi's sarcoma-associated herpesvirus (KSHV)
expressed in latently infected cells and to a higher degree during viral replication. A …

KSHV vIL-6 enhances inflammatory responses by epigenetic reprogramming

T Inagaki, KH Wang, A Kumar, C Izumiya… - PLoS …, 2023 - journals.plos.org
Kaposi sarcoma-associated herpesvirus (KSHV) inflammatory cytokine syndrome (KICS) is
a newly described chronic inflammatory disease condition caused by KSHV infection and is …

Modulation of Kaposi's sarcoma-associated herpesvirus interleukin-6 function by hypoxia-upregulated protein 1

L Giffin, F Yan, MB Major, B Damania - Journal of virology, 2014 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV, also called human herpesvirus 8) is
linked to the development of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and …

Molecular biology of KSHV in relation to HIV/AIDS-associated oncogenesis

M He, F Cheng, SR da Silva, B Tan, O Sorel… - HIV/AIDS-Associated …, 2019 - Springer
Discovered in 1994, Kaposi's sarcoma-associated herpesvirus (KSHV) has been associated
with four human malignancies including Kaposi's sarcoma, primary effusion lymphoma, a …

Kaposi's sarcoma-associated herpesvirus interleukin-6 modulates endothelial cell movement by upregulating cellular genes involved in migration

L Giffin, JA West, B Damania - MBio, 2015 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of human Kaposi's
sarcoma, a tumor that arises from endothelial cells, as well as two B cell lymphoproliferative …