Autophagy in animal development

EA Allen, EH Baehrecke - Cell Death & Differentiation, 2020 - nature.com
Macroautophagy (autophagy) delivers intracellular constituents to the lysosome to promote
catabolism. During development in multiple organisms, autophagy mediates various cellular …

Autophagy and its role in regeneration and remodeling within invertebrate

Q Song, H Liu, H Zhen, B Zhao - Cell & Bioscience, 2020 - Springer
Background Acting as a cellular cleaner by packaging and transporting defective proteins
and organelles to lysosomes for breakdown, autophagic process is involved in the …

Mining differentially expressed genes during paratomy in the transcriptome of the flatworm Stenostomum leucops

MT da Rosa, ELS Loreto - Scientific Reports, 2024 - nature.com
Paratomy is an asexual reproductive process that occurs in annelids, flatworms and other
groups. During this process, anterior structures are formed in the middle of the body, giving …

Aspirin inhibits stem cell proliferation during freshwater Dugesia japonica regeneration by STAT3/SOX2/OCT4 signaling pathway

A Liang, F Wu, C Li, Y Yu, Z Dong, G Chen, F Yu… - Aquatic Toxicology, 2022 - Elsevier
As a widely used drug in clinical practice, aspirin has a large number of residual drugs and
metabolites discharged into the environment during the pharmaceutical process or after …

Stem cells (neoblasts) and positional information jointly dominate regeneration in planarians

X Chen - Heliyon, 2025 - cell.com
Regeneration is the ability to accurately regrow missing body parts. The unparalleled
regenerative capacity and incredible tissue plasticity of planarians, both resulting from the …

Djmek is involved in planarian regeneration by regulation of cell proliferation and apoptosis

Q Wang, Y Liu, B Jin, Z Dong, G Chen, D Liu - Biochemical and Biophysical …, 2020 - Elsevier
Dugesia japonica, belonging to Platyhelminthes, plays an important role in the animal
evolution and is well known for its extraordinary regenerative ability. Mitogen activated …

Screening of potential key transcripts involved in planarian regeneration and analysis of its regeneration patterns by pacbio long-read sequencing

Y Yang, P Wang, B Jin, Z Dong, G Chen, D Liu - Frontiers in genetics, 2020 - frontiersin.org
Dugesia japonica is an excellent animal model for studying the regeneration mechanism
due to its characteristics of rapid regeneration and easy breeding. PacBio sequencing was …

[HTML][HTML] de novo transcriptome profile of two earthworms Lampito mauritii and Drawida calebi during regeneration

R Sahu, SK Sahu, SS Nishank - Biochemistry and Biophysics Reports, 2021 - Elsevier
Earthworms have remarkable ability to regenerate its tail and head region. However the list
of genes expressed in this regeneration process has been less explored baring a few …

[PDF][PDF] A comprehensive review: Research status and trends of planarianology in China

H Zhang, J He, C Shi, G Chen, D Liu - Zoological Systematics, 2023 - zootax.com.cn
Planarian is an excellent model for studying several scientific issues, and planarianology
has become an active research field in the world. Researchers at home and abroad have …

DjApi5 is required for homeostasis in planarian Dugesia japonica

S Liu, M Chen, X Liu, K Zheng, B Liu, W Wu… - Biochemical and …, 2022 - Elsevier
Orchestrated apoptosis in planarian Dugesia japonica is very important for its degrowth and
regeneration. Apoptosis Inhibitor-5 (API5) is an anti-apoptotic factor that negatively regulates …