Neurotoxicity of methamphetamine: Main effects and mechanisms

S Jayanthi, AP Daiwile, JL Cadet - Experimental neurology, 2021 - Elsevier
Methamphetamine (METH) is an illicit psychostimulant that is abused throughout the world.
METH addiction is also a major public health concern and the abuse of large doses of the …

[HTML][HTML] Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: potential therapeutic impacts

AP Daiwile, S Jayanthi, JL Cadet - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Methamphetamine (METH) use, and misuse are associated with severe socioeconomic
consequences. METH users develop tolerance, lose control over drug taking behaviors, and …

Npas4: linking neuronal activity to memory

X Sun, Y Lin - Trends in neurosciences, 2016 - cell.com
Immediate-early genes (IEGs) are rapidly activated after sensory and behavioral experience
and are believed to be crucial for converting experience into long-term memory. Neuronal …

Epigenetics of stress, addiction, and resilience: therapeutic implications

JL Cadet - Molecular neurobiology, 2016 - Springer
Substance use disorders (SUDs) are highly prevalent. SUDs involve vicious cycles of binges
followed by occasional periods of abstinence with recurrent relapses despite treatment and …

[HTML][HTML] Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies

P Shrestha, N Katila, S Lee, JH Seo, JH Jeong… - Biomedicine & …, 2022 - Elsevier
Methamphetamine (MA) is a extremely addictive psychostimulant drug with a significant
abuse potential. Long-term MA exposure can induce neurotoxic effects through oxidative …

Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model

X Zhu, Q Li, R Chang, D Yang, Z Song, Q Guo… - PloS one, 2014 - journals.plos.org
The management of neuropathic pain is still a major challenge because of its
unresponsiveness to most common treatments. Curcumin has been reported to play an …

Neuroepigenetics and addiction

DM Walker, EJ Nestler - Handbook of clinical neurology, 2018 - Elsevier
Drug addiction involves long-term behavioral abnormalities that arise in response to
repeated exposure to drugs of abuse in vulnerable individuals. It is a multifactorial syndrome …

Multiple myeloma: challenges encountered and future options for better treatment

S Das, N Juliana, NAA Yazit, S Azmani… - International Journal of …, 2022 - mdpi.com
Multiple myeloma (MM) is a malignant hematological disease. The disease is characterized
by the clonal proliferation of malignant plasma cells in the bone marrow. MM accounts for …

Epigenetic effects induced by methamphetamine and methamphetamine‐dependent oxidative stress

F Limanaqi, S Gambardella, F Biagioni… - Oxidative medicine …, 2018 - Wiley Online Library
Methamphetamine is a widely abused drug, which possesses neurotoxic activity and
powerful addictive effects. Understanding methamphetamine toxicity is key beyond the field …

Epigenetic landscape of amphetamine and methamphetamine addiction in rodents

A Godino, S Jayanthi, JL Cadet - Epigenetics, 2015 - Taylor & Francis
Amphetamine and methamphetamine addiction is described by specific behavioral
alterations, suggesting long-lasting changes in gene and protein expression within specific …