Nitric oxide (NO) is synthesized by a family of NO synthases (NOS), including neuronal,
inducible, and endothelial NOS (n/i/eNOS). NO-mediated effects can be beneficial or …

Obstructive nephropathy is characterized by an inflammatory state in the kidney, that is
promoted by cytokines and growth factors produced by damaged tubular cells, infiltrated …

This study determined effects of dietary supplementation with l-arginine (Arg) or N-
carbamylglutamate (NCG) on intestinal health and growth in early-weaned pigs. Eighty-four …

Insulin resistance (IR) is present in pathologies such as diabetes, obesity, metabolic
syndrome, impaired glucose tolerance, hypertension, inflammation, cardiac disease, and …

Ureteropelvic junction (UPJ) obstruction is the most frequently observed cause of obstructive
nephropathy in children. Neonatal and foetal animal models have been developed that …

Perturbation of renal tubular antioxidants and overproduction of reactive oxygen species
may amplify the proinflammatory state of renal obstruction, culminating in oxidative stress …

Urinary heat shock protein 70 (Hsp70) is rapidly increased in patients with clinical acute
kidney injury, indicating that it constitutes a component of the endogenous stress response …

Cardiovascular disease is currently not adequately managed and has become one of the
main causes of morbidity and mortality worldwide. Current therapies are inadequate in terms …

Background Cardiovascular inflammation and oxidative stress are determining factors in
high blood pressure and arrhythmias. Indole-3-carbinol is a cruciferous-derived …

Kidney apoptosis and fibrosis are an inevitable outcome of progressive chronic kidney
diseases where congenital obstructive nephropathy is the primary cause of the end-stage …