Short-term plasticity (STP) denotes changes in synaptic strength that last up to tens of
seconds. It is generally thought that STP impacts information transfer across synaptic …

Endocannabinoids are widely regarded as negative modulators of presynaptic release.
Here, we present evidence that in visual cortex endocannabinoids are crucial for the …

Short-term changes in synaptic gain support information processing throughout the CNS, yet
we know little about the developmental regulation of such plasticity. Here we report that …

During neocortical development, network activity undergoes a dramatic transition from
largely synchronized, so-called cluster activity, to a relatively sparse pattern around the time …

Neural circuits are composed of mainly glutamatergic and GABAergic neurons, which
communicate through synaptic connections. Many factors instruct the formation and function …

Endocannabinoids, signaling through the cannabinoid CB1 receptor (CB1R), regulate
several forms of neuronal plasticity. CB1Rs in the developing primary visual cortex (V1) play …

Visually induced endocannabinoid‐mediated long‐term depression of GABA ergic
neurotransmission (iLTD) mediates the maturation of GABA ergic release in layer 2/3 of …

Objective (s): There are few reports have demonstrated the effect of a change-in-light
experience on the structure and function of hippocampus. A change-in-light experience also …

Among the GABAergic neocortical interneurons, parvalbumin-containing fast-spiking (FS)
basket cells are essential mediators of feed-forward inhibition, network synchrony and …

Summary and Introduction Neuronal circuits are shaped by experience. This happens much
more readily in the young compared to the adult brain. The unique learning capacity of the …