Mechanisms of regulation of SNF1/AMPK/SnRK1 protein kinases

P Crozet, L Margalha, A Confraria… - Frontiers in plant …, 2014 - frontiersin.org
The SNF1 (sucrose non-fermenting 1)-related protein kinases 1 (SnRKs1) are the plant
orthologs of the budding yeast SNF1 and mammalian AMPK (AMP-activated protein kinase) …

The roles of ubiquitin in mediating autophagy

Z Yin, H Popelka, Y Lei, Y Yang, DJ Klionsky - Cells, 2020 - mdpi.com
Ubiquitination, the post-translational modification essential for various intracellular
processes, is implicated in multiple aspects of autophagy, the major lysosome/vacuole …

The plant energy sensor: evolutionary conservation and divergence of SnRK1 structure, regulation, and function

T Broeckx, S Hulsmans, F Rolland - Journal of experimental …, 2016 - academic.oup.com
Abstract The SnRK1 (SNF1-related kinase 1) kinases are the plant cellular fuel gauges,
activated in response to energy-depleting stress conditions to maintain energy homeostasis …

Functions of SAGA in development and disease

L Wang, S YR Dent - Epigenomics, 2014 - Taylor & Francis
Precise regulation of gene expression programs during embryo development requires
cooperation between transcriptional factors and histone-modifying enzymes, such as the …

SnRK1 inhibits anthocyanin biosynthesis through both transcriptional regulation and direct phosphorylation and dissociation of the MYB/bHLH/TTG1 MBW complex

E Broucke, TTV Dang, Y Li, S Hulsmans… - The Plant …, 2023 - Wiley Online Library
Plants have evolved an extensive specialized secondary metabolism. The colorful flavonoid
anthocyanins, for example, not only stimulate flower pollination and seed dispersal, but also …

[HTML][HTML] Conventional and emerging roles of the energy sensor Snf1/AMPK in Saccharomyces cerevisiae

P Coccetti, R Nicastro, F Tripodi - Microbial Cell, 2018 - ncbi.nlm.nih.gov
All proliferating cells need to match metabolism, growth and cell cycle progression with
nutrient availability to guarantee cell viability in spite of a changing environment. In yeast, a …

[HTML][HTML] Ubiquitin-specific peptidase 22 functions and its involvement in disease

J Melo-Cardenas, Y Zhang, DD Zhang, D Fang - Oncotarget, 2016 - ncbi.nlm.nih.gov
Deubiquitylases remove ubiquitin moieties from different substrates to regulate protein
activity and cell homeostasis. Since this posttranslational modification plays a role in several …

The structure and function of deubiquitinases: lessons from budding yeast

HG Suresh, N Pascoe, B Andrews - Open biology, 2020 - royalsocietypublishing.org
Protein ubiquitination is a key post-translational modification that regulates diverse cellular
processes in eukaryotic cells. The specificity of ubiquitin (Ub) signalling for different …

Ubiquitin-specific peptidase 22 in cancer

T Feng, S Ling, C Xu, L Ying, D Su, X Xu - Cancer letters, 2021 - Elsevier
Recently, many studies have shown that deubiquitination modification of proteins is of great
significance in major physiological processes such as cell proliferation, apoptosis, and …

Non-histone protein acetylation by the evolutionarily conserved GCN5 and PCAF acetyltransferases

M Downey - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2021 - Elsevier
GCN5, conserved from yeast to humans, and the vertebrate specific PCAF, are lysine
acetyltransferase enzymes found in large protein complexes. Both enzymes have well …