Acute head-fixed recordings in awake mice with multiple Neuropixels probes

S Durand, GR Heller, TK Ramirez, JA Luviano… - Nature …, 2023 - nature.com
Multi-electrode arrays such as Neuropixels probes enable electrophysiological recordings
from large populations of single neurons with high temporal resolution. By using such …

Forty-hertz light stimulation does not entrain native gamma oscillations in Alzheimer's disease model mice

M Soula, A Martín-Ávila, Y Zhang, A Dhingra… - Nature …, 2023 - nature.com
There is a demand for noninvasive methods to ameliorate disease. We investigated whether
40-Hz flickering light entrains gamma oscillations and suppresses amyloid-β in the brains of …

Spike sorting: new trends and challenges of the era of high-density probes

AP Buccino, S Garcia, P Yger - Progress in Biomedical …, 2022 - iopscience.iop.org
Recording from a large neuronal population of neurons is a crucial challenge to unravel how
information is processed by the brain. In this review, we highlight the recent advances made …

Associative and predictive hippocampal codes support memory-guided behaviors

C Liu, R Todorova, W Tang, A Oliva, A Fernandez-Ruiz - Science, 2023 - science.org
Episodic memory involves learning and recalling associations between items and their
spatiotemporal context. Those memories can be further used to generate internal models of …

Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis

R Huszár, Y Zhang, H Blockus, G Buzsáki - Nature Neuroscience, 2022 - nature.com
The incorporation of new information into the hippocampal network is likely to be
constrained by its innate architecture and internally generated activity patterns. However, the …

Hippocampo-cortical circuits for selective memory encoding, routing, and replay

RE Harvey, HL Robinson, C Liu, A Oliva… - Neuron, 2023 - cell.com
Traditionally considered a homogeneous cell type, hippocampal pyramidal cells have been
recently shown to be highly diverse. However, how this cellular diversity relates to the …

A hippocampal circuit mechanism to balance memory reactivation during sleep

LA Karaba, HL Robinson, RE Harvey, W Chen… - Science, 2024 - science.org
Memory consolidation involves the synchronous reactivation of hippocampal cells active
during recent experience in sleep sharp-wave ripples (SWRs). How this increase in firing …

Id2 GABAergic interneurons comprise a neglected fourth major group of cortical inhibitory cells

R Machold, S Dellal, M Valero, H Zurita, I Kruglikov… - elife, 2023 - elifesciences.org
Abstract Cortical GABAergic interneurons (INs) represent a diverse population of mainly
locally projecting cells that provide specialized forms of inhibition to pyramidal neurons and …

Flexible neural population dynamics govern the speed and stability of sensory encoding in mouse visual cortex

EAB Horrocks, FR Rodrigues, AB Saleem - Nature Communications, 2024 - nature.com
Time courses of neural responses underlie real-time sensory processing and perception.
How these temporal dynamics change may be fundamental to how sensory systems adapt …

Extrinsic control and intrinsic computation in the hippocampal CA1 circuit

I Zutshi, M Valero, A Fernández-Ruiz, G Buzsáki - Neuron, 2022 - cell.com
In understanding circuit operations, a key problem is the extent to which neuronal spiking
reflects local computation or responses to upstream inputs. We addressed this issue in the …