Antimicrobial resistance surveillance in low-and middle-income countries: progress and challenges in eight South Asian and Southeast Asian countries

S Gandra, G Alvarez-Uria, P Turner… - Clinical Microbiology …, 2020 - Am Soc Microbiol
Antimicrobial resistance (AMR) is a serious global health threat and is predicted to cause
significant health and economic impacts, particularly in low-and middle-income countries …

Carbapenem and colistin resistance in Enterobacteriaceae in Southeast Asia: review and mapping of emerging and overlapping challenges

MD Malchione, LM Torres, DM Hartley, M Koch… - International journal of …, 2019 - Elsevier
Carbapenem-resistant Enterobacteriaceae infections have spread globally, leaving
polymyxins, including colistin, as 'last-resort treatments'. Emerging colistin resistance raises …

Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

KL Wyres, TNT Nguyen, MMC Lam, LM Judd… - Genome medicine, 2020 - Springer
Background Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI).
Strains producing extended-spectrum beta-lactamases (ESBLs) or carbapenemases are …

The role of the light source in antimicrobial photodynamic therapy

M Piksa, C Lian, IC Samuel, KJ Pawlik… - Chemical Society …, 2023 - pubs.rsc.org
Antimicrobial photodynamic therapy (APDT) is a promising approach to fight the growing
problem of antimicrobial resistance that threatens health care, food security and agriculture …

Emerging resistance to empiric antimicrobial regimens for pediatric bloodstream infections in Malawi (1998–2017)

PY Iroh Tam, P Musicha, K Kawaza… - Clinical Infectious …, 2019 - academic.oup.com
Background The adequacy of the World Health Organization's Integrated Management of
Childhood Illness (IMCI) antimicrobial guidelines for the treatment of suspected severe …

Microbiology Investigation Criteria for Reporting Objectively (MICRO): a framework for the reporting and interpretation of clinical microbiology data

P Turner, A Fox-Lewis, P Shrestha, DAB Dance… - BMC medicine, 2019 - Springer
Background There is a pressing need to understand better the extent and distribution of
antimicrobial resistance on a global scale, to inform development of effective interventions …

[HTML][HTML] Surveillance strategies using routine microbiology for antimicrobial resistance in low-and middle-income countries

C Lim, EA Ashley, RL Hamers, P Turner… - Clinical Microbiology …, 2021 - Elsevier
Background Routine microbiology results are a valuable source of antimicrobial resistance
(AMR) surveillance data in low-and middle-income countries (LMICs) as well as in high …

[HTML][HTML] Using machine learning to guide targeted and locally-tailored empiric antibiotic prescribing in a children's hospital in Cambodia

M Oonsivilai, Y Mo, N Luangasanatip… - Wellcome open …, 2018 - ncbi.nlm.nih.gov
Background: Early and appropriate empiric antibiotic treatment of patients suspected of
having sepsis is associated with reduced mortality. The increasing prevalence of …

Leapfrogging laboratories: the promise and pitfalls of high-tech solutions for antimicrobial resistance surveillance in low-income settings

IN Okeke, N Feasey, J Parkhill, P Turner… - BMJ global …, 2020 - gh.bmj.com
The scope and trajectory of today's escalating antimicrobial resistance (AMR) crisis is
inadequately captured by existing surveillance systems, particularly those of lower income …

MgrB-dependent colistin resistance in Klebsiella pneumoniae is associated with an increase in host-to-host transmission

AS Bray, RD Smith, AW Hudson, GE Hernandez… - MBio, 2022 - Am Soc Microbiol
Due to its high transmissibility, Klebsiella pneumoniae is one of the leading causes of
nosocomial infections. Here, we studied the biological cost of colistin resistance, an …