Valproic Acid–Associated Hyperammonemia: A Systematic Review
YCJ Wong, J Fan, A Wan, T Mihic… - Journal of Clinical …, 2023 - journals.lww.com
Background Hyperammonemia is an adverse effect that poses clinical uncertainty around
valproic acid (VPA) use. The prevalence of symptomatic and asymptomatic …
valproic acid (VPA) use. The prevalence of symptomatic and asymptomatic …
[HTML][HTML] Blood levels of ammonia and carnitine in patients treated with valproic acid: a meta-analysis
S Yokoyama, N Sugawara, K Maruo… - Clinical …, 2022 - ncbi.nlm.nih.gov
Objective Long-term valproic acid (VPA) administration is associated with adverse metabolic
effects, including hyperammonemia and hypocarnitinemia. However, the pathogeneses of …
effects, including hyperammonemia and hypocarnitinemia. However, the pathogeneses of …
Is Prenatal Valproate Exposure a Risk Factor for Autism
DS Reddy, J Brewer, M Manchi - International Journal of …, 2018 - ijpsnonline.com
Sodium valproate (Depakene) and divalproex sodium (Depakote) are two commonly used
drugs for epilepsy therapy. Sodium valproate, a first-generation antiepileptic drug, has …
drugs for epilepsy therapy. Sodium valproate, a first-generation antiepileptic drug, has …
The Effect of Carnitine Supplementation on Blood Ammonia Level in Epilepsy Children Treated with Valproic Acid: A Randomized Controlled Trial
Background: Long-term use of valproic acid is associated with a high level of blood
ammonia related to carnitine deficiency. This study investigates the effect of carnitine …
ammonia related to carnitine deficiency. This study investigates the effect of carnitine …
[PDF][PDF] Valproate induced hyperammonemia with deranged liver function
R Tripathy, JK Majhi, MR Pradhan - Asian J Pharm Clin Res, 2015 - Citeseer
Valproate is one of the most prescribed anti-epileptic drugs. It could cause a rise in serum
ammonia level in patients, especially children and young adults. This presents with altered …
ammonia level in patients, especially children and young adults. This presents with altered …
High Blood Ammonia Levels Associated with Long-term Valproic Acids Therapy in Epileptic Children
Background: Valproic acid is an effective drug for controlling seizure in children with
epilepsy and it is usually used for treatment as long as two years or more. Blood ammonia …
epilepsy and it is usually used for treatment as long as two years or more. Blood ammonia …
[PDF][PDF] Prospective Observational Study of Sodium Valproate in Seizure Control and Associated Adverse Drug Reactions in Pediatric Population
K Vasudev - academia.edu
Sodium valproate is a commonly used antiepileptic drug for control of broad range of
seizures. Adverse drug reactions (ADR) due to valproate widely range from severe to less …
seizures. Adverse drug reactions (ADR) due to valproate widely range from severe to less …