Identification of a novel DNA repair inhibitor using an in silico driven approach shows effective combinatorial activity with genotoxic agents against multidrug‐resistant …
Increasing antimicrobial drug resistance represents a global existential threat. Infection is a
particular problem in immunocompromised individuals, such as patients undergoing cancer …
particular problem in immunocompromised individuals, such as patients undergoing cancer …
Deep learning-based prediction of chemical accumulation in a pathogenic mycobacterium
MR Sullivan, EJ Rubin - bioRxiv, 2024 - biorxiv.org
Drugs must accumulate at their target site to be effective, and inadequate uptake of drugs is
a substantial barrier to the design of potent therapies. This is particularly true in the …
a substantial barrier to the design of potent therapies. This is particularly true in the …