Sex and gender differences in cognitive resilience to aging and Alzheimer's disease

EM Arenaza‐Urquijo, R Boyle, K Casaletto… - Alzheimer's & …, 2024 - Wiley Online Library
Sex and gender—biological and social constructs—significantly impact the prevalence of
protective and risk factors, influencing the burden of Alzheimer's disease (AD; amyloid beta …

Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective

MM Mielke, NT Aggarwal, C Vila‐Castelar… - Alzheimer's & …, 2022 - Wiley Online Library
Sex or gender differences in the risk of Alzheimer's disease and related dementias (ADRD)
differ by world region, suggesting that there are potentially modifiable risk factors for …

Earlier Detection of Alzheimer's Disease Based on a Novel Biomarker cis P-tau by a Label-Free Electrochemical Immunosensor

A Shiravandi, F Yari, N Tofigh, M Kazemi Ashtiani… - Biosensors, 2022 - mdpi.com
Early detection of cis phosphorylated tau (cis P-tau) may help as an effective treatment to
control the progression of Alzheimer's disease (AD). Recently, we introduced for the first time …

Relationship of sex differences in cortical thickness and memory among cognitively healthy subjects and individuals with mild cognitive impairment and Alzheimer …

F Cieri, X Zhuang, D Cordes, N Kaplan… - Alzheimer's research & …, 2022 - Springer
Background An aging society has increased rates of late onset Alzheimer disease dementia
(ADD), the most common form of age-related dementia. This neurodegenerative disease …

Plasma phosphorylated tau‐217 exhibits sex‐specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults

R Saloner, L VandeVrede, BM Asken… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Accumulating evidence indicates disproportionate tau burden and tau‐
related clinical progression in females. However, sex differences in plasma phosphorylated …

The effects of brain magnetic resonance imaging indices in the Association of Olfactory Identification and Cognition in Chinese older adults

Z Tan, Y Wang, H Lu, W Tian, K Xu, M Fan… - Frontiers in Aging …, 2022 - frontiersin.org
Background Olfactory identification dysfunction frequently occurs in individuals with
cognitive decline; however, a pathological mechanism linking the two has not been …

Sex differences in cognitive resilience in preclinical autosomal‐dominant Alzheimer's disease carriers and non‐carriers: baseline findings from the API ADAD …

C Vila‐Castelar, PN Tariot, KM Sink… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Females may have greater susceptibility to Alzheimer's disease (AD)‐
pathology. We examined the effect of sex on pathology, neurodegeneration, and memory in …

Machine learning methods to predict amyloid positivity using domain scores from cognitive tests

G Shan, C Bernick, JZK Caldwell, A Ritter - Scientific Reports, 2021 - nature.com
Amyloid-β (A β) is the target in many clinical trials for Alzheimer's disease (AD). Preclinical
AD patients are heterogeneous with regards to different backgrounds and diagnosis …

The neuroanatomic correlates of olfactory identification impairment in healthy older adults and in persons with mild cognitive impairment

V Kamath, ML Senjem, AJ Spychalla… - Journal of …, 2022 - content.iospress.com
Background: Olfactory identification (OI) impairment appears early in the course of
Alzheimer's disease dementia (AD), prior to detectable cognitive impairment. However, the …

Examining sex differences in markers of cognition and neurodegeneration in autosomal dominant Alzheimer's disease: Preliminary findings from the Colombian …

C Vila-Castelar, E Guzmán-Vélez… - Journal of …, 2020 - content.iospress.com
Background: Growing evidence suggests that there may be a sex-specific biological risk for
Alzheimer's disease (AD). Individuals with autosomal dominant AD due to a mutation …