Inhibition of lysophosphatidic acid receptor 1 attenuates neuroinflammation via PGE2/EP2/NOX2 signalling and improves the outcome of intracerebral haemorrhage …

L Gao, H Shi, P Sherchan, H Tang, L Peng… - Brain, behavior, and …, 2021 - Elsevier
Abstract Lysophosphatidic acid receptor 1 (LPA1) plays a critical role in proinflammatory
processes in the central nervous system by modulating microglia activation. The aim of this …

MicroPET imaging assessment of brain tau and amyloid deposition in 6× Tg Alzheimer's disease model mice

SW Kang, J Kim, SY Lee, N Okamura… - International Journal of …, 2022 - mdpi.com
Alzheimer's disease (AD) is characterized by the deposition of extracellular amyloid plaques
and intracellular accumulation of neurofibrillary tangles (NFT). Amyloid beta (Aβ) and tau …

Usefulness of postoperative serum translocator protein as a predictive marker for delirium after breast cancer surgery in elderly women

GW Lu, YE Chou, WL Jin, XB Su - Journal of International …, 2020 - journals.sagepub.com
Objective Postoperative delirium (POD) has rarely been investigated in breast cancer
patients. Herein, we assessed the association between serum levels of the inflammatory …

The Design, Synthesis and Evaluation of Novel CB2 Ligands

A Kallinen - 2019 - ses.library.usyd.edu.au
The pathophysiology of brain injury and a variety of neurodegenerative diseases involves
an inflammation cascade that causes neuronal loss and damage in the central nervous …