Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …

Cell-to-cell communication and cell fusion are fundamental biological processes across the
tree of life. Survival is often dependent upon being able to identify nearby individuals and …

Fungal hyphae extend by apical growth. This process involves the polarized traffic of
secretory vesicles to the Spitzenkörper (SPK) and their subsequent distribution to specific …

Hyphae represent a hallmark structure of multicellular fungi. The evolutionary origins of
hyphae and of the underlying genes are, however, hardly known. By systematically …

The striatin-interacting phosphatases and kinases (STRIPAK) complex is evolutionary highly
conserved and has been structurally and functionally described in diverse lower and higher …

Highlights•The Spitzenkörper (SPK) is a highly ordered structure of hyphal apices.•The SPK
determines hyphal growth and morphogenesis.•Neurospora crassa provides insight into the …

The Spitzenkörper (SPK) constitutes a collection of secretory vesicles and polarity-related
proteins intimately associated with polarized growth of fungal hyphae. Many SPK-localized …

In filamentous fungi, hyphal growth depends on the continuous delivery of vesicles to the
growing tips. It is unclear how fast‐growing hyphae coordinate simultaneous cell extension …

The main model for studying the mechanistic basis of hyphal self-fusion is the conidial
anastomosis tube (CAT) system of Neurospora crassa. CATs are specialized cell …

Growth and propagation of filamentous ascomycete fungi commonly involves vegetative cell
fusion. In the red bread mold Neurospora crassa and many other ascomycete species …