D Gao, F Jin, M Zhou, Y Jiang - Analyst, 2019 - pubs.rsc.org
Single cell analysis has become of great interest with unprecedented capabilities for the systematic investigation of cell-to-cell variation in large populations. Rapid and multi …
SD Ling, Y Geng, A Chen, Y Du, J Xu - Biomicrofluidics, 2020 - pubs.aip.org
Single-cell analysis to investigate cellular heterogeneity and cell-to-cell interactions is a crucial compartment to answer key questions in important biological mechanisms. Droplet …
H Chai, Y Feng, F Liang, W Wang - Lab on a Chip, 2021 - pubs.rsc.org
Successful single-cell isolation is a pivotal technique for subsequent biological and chemical analysis of single cells. Although significant advances have been made in single …
This Feature describes the different particle manipulation techniques available in the droplet microfluidics toolbox to handle particles encapsulated inside droplets and to manipulate …
Single-cell patterning technologies are rapidly evolving, where single cells are positioned in spatially distinct areas, thus providing a platform for several biological and biomedical …
F Ahmadi, H Tran, N Letourneau, SR Little, A Fortin… - Small, 2024 - Wiley Online Library
Monoclonal antibody (mAb) discovery plays a prominent role in diagnostic and therapeutic applications. Droplet microfluidics has become a standard technology for high‐throughput …
Generating a stable knockout cell line is a complex process that can take several months to complete. In this work, a microfluidic method that is capable of isolating single cells in …
M Yu, YJ Li, YN Yang, CD Xue, GY Xin, B Liu, KR Qin - Talanta, 2024 - Elsevier
Microfluidic-based analyses of single-cell dynamics in response to dynamic biochemical signals are emerging as pivotal approaches for investigating the effects of extracellular …
L Armbrecht, G Gabernet, F Kurth, JA Hiss… - Lab on a Chip, 2017 - pubs.rsc.org
The development of efficacious anticancer therapeutics is difficult due to the heterogeneity of the cellular response to chemotherapy. Anticancer peptides (ACPs) are promising drug …