Myelin oligodendrocyte glycoprotein antibodies in neurological disease
Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Abs) were first detected
by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their …
by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their …
Multiple sclerosis: experimental models and reality
H Lassmann, M Bradl - Acta neuropathologica, 2017 - Springer
One of the most frequent statements, provided in different variations in the introduction of
experimental studies on multiple sclerosis (MS), is that “Multiple sclerosis is a demyelinating …
experimental studies on multiple sclerosis (MS), is that “Multiple sclerosis is a demyelinating …
The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells
J Machado-Santos, E Saji, AR Tröscher, M Paunovic… - Brain, 2018 - academic.oup.com
Multiple sclerosis is an inflammatory demyelinating disease in which active demyelination
and neurodegeneration are associated with lymphocyte infiltrates in the brain. However, so …
and neurodegeneration are associated with lymphocyte infiltrates in the brain. However, so …
The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody
We sought to define the pathological features of myelin oligodendrocyte glycoprotein (MOG)
antibody associated disorders (MOGAD) in an archival autopsy/biopsy cohort. We …
antibody associated disorders (MOGAD) in an archival autopsy/biopsy cohort. We …
Myelin oligodendrocyte glycoprotein antibody-associated disease: an immunopathological study
Y Takai, T Misu, K Kaneko, N Chihara, K Narikawa… - Brain, 2020 - academic.oup.com
Conformation-sensitive antibodies against myelin oligodendrocyte glycoprotein (MOG) are
detectable in patients with optic neuritis, myelitis, opticomyelitis, acute or multiphasic …
detectable in patients with optic neuritis, myelitis, opticomyelitis, acute or multiphasic …
Pathological mechanisms in progressive multiple sclerosis
DH Mahad, BD Trapp, H Lassmann - The Lancet Neurology, 2015 - thelancet.com
A better understanding of the pathological mechanisms that drive neurodegeneration in
individuals with multiple sclerosis is needed to develop therapies that will effectively treat …
individuals with multiple sclerosis is needed to develop therapies that will effectively treat …
Role of the innate and adaptive immune responses in the course of multiple sclerosis
Multiple sclerosis is a chronic disease of the CNS that leads to substantial disability in most
patients. The early phase is characterised by relapses and the later phase by progressive …
patients. The early phase is characterised by relapses and the later phase by progressive …
Neurological update: MOG antibody disease
R Wynford-Thomas, A Jacob, V Tomassini - Journal of neurology, 2019 - Springer
Myelin oligodendrocyte glycoprotein (MOG) antibody disease (MOG-AD) is now recognised
as a nosological entity with specific clinical and paraclinical features to aid early diagnosis …
as a nosological entity with specific clinical and paraclinical features to aid early diagnosis …
The clinical spectrum and incidence of anti-MOG-associated acquired demyelinating syndromes in children and adults
CL De Mol, YYM Wong, ED Van Pelt… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Objectives: The aim of this study was to assess the Dutch nationwide incidence of myelin
oligodendrocyte glycoprotein (MOG)-IgG-associated acquired demyelinating syndromes …
oligodendrocyte glycoprotein (MOG)-IgG-associated acquired demyelinating syndromes …
Progressive multiple sclerosis: pathology and pathogenesis
H Lassmann, J Van Horssen, D Mahad - Nature Reviews Neurology, 2012 - nature.com
Major progress has been made during the past three decades in understanding the
inflammatory process and pathogenetic mechanisms in multiple sclerosis (MS) …
inflammatory process and pathogenetic mechanisms in multiple sclerosis (MS) …