Role of patient-derived models of cancer in translational oncology
KF Idrisova, HU Simon, MO Gomzikova - Cancers, 2022 - mdpi.com
Simple Summary It was found that long-established tumor-derived cell lines do not
adequately reproduce drug sensitivity and behavior of a real human cancers. Therefore …
adequately reproduce drug sensitivity and behavior of a real human cancers. Therefore …
Mechanical studies of the third dimension in cancer: From 2D to 3D model
F Paradiso, S Serpelloni, LW Francis… - International Journal of …, 2021 - mdpi.com
From the development of self-aggregating, scaffold-free multicellular spheroids to the
inclusion of scaffold systems, 3D models have progressively increased in complexity to …
inclusion of scaffold systems, 3D models have progressively increased in complexity to …
Visible light photocrosslinking of sugar beet pectin for 3D bioprinting applications
Herein, we report the hydrogelation of sugar beet pectin (SBP) via visible light-mediated
photocrosslinking and its applications in extrusion-based 3D bioprinting. Rapid …
photocrosslinking and its applications in extrusion-based 3D bioprinting. Rapid …
Glioblastoma spheroid growth and chemotherapeutic responses in single and dual-stiffness hydrogels
J Bruns, T Egan, P Mercier, SP Zustiak - Acta Biomaterialia, 2023 - Elsevier
Glioblastoma (GBM) is the deadliest brain tumor for which there is no cure. Bioengineered
GBM models, such as hydrogel-encapsulated spheroids, that capture both cell-cell and cell …
GBM models, such as hydrogel-encapsulated spheroids, that capture both cell-cell and cell …
In Situ Fabrication of Constraints for Multicellular Micro‐Spheroids Using Two‐Photon Lithography
M Taale, B Schamberger, F Taheri… - Advanced Functional …, 2024 - Wiley Online Library
photon polymerization is a promising technology for creating complex, microscale 3D
matrices for biomedical and also bioprinting applications. Cancer research provides …
matrices for biomedical and also bioprinting applications. Cancer research provides …
Enhancing nanoparticle accumulation in two dimensional, three dimensional, and xenograft mouse cancer cell models in the presence of docetaxel
K Bromma, N Dos Santos, I Barta, A Alexander… - Scientific Reports, 2022 - nature.com
Recent clinical trials show docetaxel (DTX), given in conjunction with radiation therapy (RT)
and androgen suppression, improves survival in high-risk prostate cancer. Addition of gold …
and androgen suppression, improves survival in high-risk prostate cancer. Addition of gold …
Utilizing two-dimensional monolayer and three-dimensional spheroids to enhance radiotherapeutic potential by combining gold nanoparticles and docetaxel
Background Much in vitro research on the applicability of gold nanoparticles (GNPs) in
cancer treatment has been focused on two-dimensional (2D) monolayer models. To improve …
cancer treatment has been focused on two-dimensional (2D) monolayer models. To improve …
Human serum albumin-poly (Lactide)-conjugated self-assembly NPs for targeted docetaxel delivery and improved therapeutic efficacy in oral cancer
Oral cancer is one of the most prevalent malignancies worldwide. Here, to prepare a
biocompatible tumor-targeted nanoformulation capable of efficient loading of the …
biocompatible tumor-targeted nanoformulation capable of efficient loading of the …
Three-Dimensional (3D) in vitro cell culture protocols to enhance glioblastoma research
Three-dimensional (3D) cell culture models can help bridge the gap between in vitro cell
cultures and in vivo responses by more accurately simulating the natural in vivo …
cultures and in vivo responses by more accurately simulating the natural in vivo …
Plasma induced reactive oxygen species‐dependent cytotoxicity in glioblastoma 3D tumourspheres
The aim of this study was to determine the effects of a pin‐to‐plate cold atmospheric plasma
(CAP) on U‐251 MG three‐dimensional (3D) glioblastoma spheroids under different …
(CAP) on U‐251 MG three‐dimensional (3D) glioblastoma spheroids under different …