In this paper, we review the evidence bearing on socio‐economic disparities in pregnancy
outcome, focusing on aetiological factors mediating the disparities in intrauterine growth …

E. Functional development 1. Ontogeny of steroidogenic activity 2. Functional zonation and
ontogeny of steroidogenic enzyme expression 3. Responsiveness to ACTH III. Regulation A …

OBJECTIVE: The aim was to test a model of the influence of maternal prenatal psychosocial
stress on birth outcomes after controlling for biomedical risk. STUDY DESIGN: In a …

We report the existence of a 'placental clock', which is active from an early stage in human
pregnancy and determines the length of gestation and the timing of parturition and delivery …

Preterm birth is associated with high rates of infant mortality and morbidity. This review
emphasizes that the onset of labor entails a molecular collaboration between the mother …

I. Introduction D uring the last 15 years our concepts of the role and functioning of
intrauterine tissues during human pregnancy have been changing. While initially considered …

abstract Estrogens produced by the placenta play a pivotal role in the endocrine control of
pregnancy and induce many of the key changes involved in parturition. The placentae of …

I. A Brief History of Corticotropin-Releasing Hormone (CRH) and Vasopressin as Mediators
of Pituitary-Adrenal Activation in Humans HARRIS'1948 hypothesis (1) that anterior pituitary …

Corticotropin-releasing hormone (CRH) derived from the placenta is secreted into the
maternal circulation in large amounts during the third trimester of human pregnancy and …

Objectives: We investigated whether maternal plasma levels of the placental hormone
corticotropin-releasing hormone are elevated in pregnancies complicated by preterm labor …