Computational strategies for dissecting the high-dimensional complexity of adaptive immune repertoires

E Miho, A Yermanos, CR Weber, CT Berger… - Frontiers in …, 2018 - frontiersin.org
The adaptive immune system recognizes antigens via an immense array of antigen-binding
antibodies and T-cell receptors, the immune repertoire. The interrogation of immune …

The phylogenomic forest of bird trees contains a hard polytomy at the root of Neoaves

A Suh - Zoologica Scripta, 2016 - Wiley Online Library
Birds have arguably been the most intensely studied animal group for their phylogenetic
relationships. However, the recent advent of genome‐scale phylogenomics has made the …

GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes

TR Ranallo-Benavidez, KS Jaron, MC Schatz - Nature communications, 2020 - nature.com
An important assessment prior to genome assembly and related analyses is genome
profiling, where the k-mer frequencies within raw sequencing reads are analyzed to estimate …

Evolview v3: a webserver for visualization, annotation, and management of phylogenetic trees

B Subramanian, S Gao, MJ Lercher, S Hu… - Nucleic acids …, 2019 - academic.oup.com
Evolview is an interactive tree visualization tool designed to help researchers in visualizing
phylogenetic trees and in annotating these with additional information. It offers the user with …

NGPhylogeny. fr: new generation phylogenetic services for non-specialists

F Lemoine, D Correia, V Lefort… - Nucleic acids …, 2019 - academic.oup.com
Abstract Phylogeny. fr, created in 2008, has been designed to facilitate the execution of
phylogenetic workflows, and is nowadays widely used. However, since its development …

[HTML][HTML] Microbial interkingdom interactions in roots promote Arabidopsis survival

P Durán, T Thiergart, R Garrido-Oter, M Agler, E Kemen… - Cell, 2018 - cell.com
Roots of healthy plants are inhabited by soil-derived bacteria, fungi, and oomycetes that
have evolved independently in distinct kingdoms of life. How these microorganisms interact …

W-IQ-TREE: a fast online phylogenetic tool for maximum likelihood analysis

J Trifinopoulos, LT Nguyen… - Nucleic acids …, 2016 - academic.oup.com
This article presents W-IQ-TREE, an intuitive and user-friendly web interface and server for
IQ-TREE, an efficient phylogenetic software for maximum likelihood analysis. W-IQ-TREE …

Evolview v2: an online visualization and management tool for customized and annotated phylogenetic trees

Z He, H Zhang, S Gao, MJ Lercher… - Nucleic acids …, 2016 - academic.oup.com
Evolview is an online visualization and management tool for customized and annotated
phylogenetic trees. It allows users to visualize phylogenetic trees in various formats …

Mutational dynamics between primary and relapse neuroblastomas

A Schramm, J Köster, Y Assenov, K Althoff, M Peifer… - Nature …, 2015 - nature.com
Neuroblastoma is a malignancy of the developing sympathetic nervous system that is often
lethal when relapse occurs. We here used whole-exome sequencing, mRNA expression …

Inferring ancient divergences requires genes with strong phylogenetic signals

L Salichos, A Rokas - Nature, 2013 - nature.com
To tackle incongruence, the topological conflict between different gene trees, phylogenomic
studies couple concatenation with practices such as rogue taxon removal or the use of …