Allopregnanolone (3α-THP) has been one of the most studied progesterone metabolites for
decades. 3α-THP and its synthetic analogs have been evaluated as therapeutic agents for …

Abstract Smoking accounts for almost 80–90% of lung cancer cases, which is also the most
frequent cause of cancer-related deaths in humans. With over 60 carcinogens in tobacco …

Glioblastoma multiforme (GBM) has been recognized as the most lethal type of malignant
brain tumor. Despite efforts of the medical and research community, patients' survival …

Background The median survival for patients with glioblastoma (GBM), the most common
primary malignant brain tumor in adults, has remained approximately 1 year for more than 2 …

Background Previous studies demonstrated that AIB1 or HER2 copy number gain (CNG),
respectively, were independent predictors for poor prognosis of glioma patients, especially …

Purpose: Patient sex is recognized as a significant determinant of outcome but the relative
prognostic importance of molecular, imaging, and other clinical features of GBM has not yet …

High dimensional data consists of matrices with a large number of features and is common
across many fields of study, including genetics, imaging, and toxicology. This type of data is …