A tutorial for model‐based evaluation and translation of cardiovascular safety in preclinical trials
V Kulesh, I Vasyutin, A Volkova… - CPT …, 2024 - Wiley Online Library
Assessment of drug‐induced effects on the cardiovascular (CV) system remains a critical
component of the drug discovery process enabling refinement of the therapeutic index …
component of the drug discovery process enabling refinement of the therapeutic index …
PBPK modeling and simulation and therapeutic drug monitoring: Possible ways for antibiotic dose adjustment
Pharmacokinetics (PK) is a branch of pharmacology present and of vital importance for the
research and development (R&D) of new drugs, post-market monitoring, and continued …
research and development (R&D) of new drugs, post-market monitoring, and continued …
On discovering treatment-effect modifiers using virtual twins and causal forest ml in the presence of prognostic biomarkers
E Hermansson, D Svensson - International Conference on Computational …, 2021 - Springer
The recent years have seen a rapid development in the general Machine Learning area and
a similar strong trend has taken place within the drug development domain, known as …
a similar strong trend has taken place within the drug development domain, known as …
Concept and utility of population pharmacokinetic and pharmacokinetic/pharmacodynamic models in drug development and clinical practice
M Roganović, A Homšek, M Jovanović… - Archives of …, 2021 - aseestant.ceon.rs
Due to frequent clinical trial failures and consequently fewer new drug approvals, the need
for improvement in drug development has, to a certain extent, been met using model-based …
for improvement in drug development has, to a certain extent, been met using model-based …
Biostatistical Investigation Using Docking Mechanism and Its Database to Investigate Drug Design, Drug Discovery, Drug Metabolism and Prediction Via Drug–Drug …
I Gulati, S Tripathi, SS Tiwari - … and Biotechnology: An Insight into Current …, 2024 - Springer
Molecular docking is an important tool for structure-based drug design and is being widely
used to study molecular interactions with proteins at atomic levels. Molecular docking, being …
used to study molecular interactions with proteins at atomic levels. Molecular docking, being …
[PDF][PDF] PBPK Modeling and Simulation and Therapeutic Drug Monitoring: Possible Ways for Antibiotic Dose Adjustment. Processes 2021, 9, 2087
Pharmacokinetics (PK) is a branch of pharmacology present and of vital importance for the
research and development (R&D) of new drugs, post-market monitoring, and continued …
research and development (R&D) of new drugs, post-market monitoring, and continued …
[引用][C] Causal Bayesian machine learning to assess the heterogeneous effect of smoking or drinking with mortality: A longitudinal analysis of Chinese Longitudinal …
T Cui - 2024 - Durham University
[引用][C] Koncept i upotreba populacionih farmakokinetičkih i farmakokinetičko/farmakodinamičkih modela u razvoju leka i kliničkoj praksi
M Roganović, A Homšek… - Arhiv za …, 2021 - … of Serbia, Belgrade and University of …