Obstructive Sleep Apnea-Associated Intermittent Hypoxia-Induced Immune Responses in Males, Pregnancies, and Offspring

R Song, TL Baker, JJ Watters, S Kumar - International Journal of …, 2024 - mdpi.com
Obstructive sleep apnea (OSA), a respiratory sleep disorder associated with cardiovascular
diseases, is more prevalent in men. However, OSA occurrence in pregnant women rises to a …

Novel Exopolysaccharide from Marine Bacillus subtilis with Broad Potential Biological Activities: Insights into Antioxidant, Anti-Inflammatory, Cytotoxicity, and Anti …

BA Abdel-Wahab, H F. Abd El-Kareem, A Alzamami… - Metabolites, 2022 - mdpi.com
In the presented study, Bacillus subtilis strain AG4 isolated from marine was identified based
on morphological, physiological, phylogenetic characteristics and an examination of 16S …

Novel 1, 3-thiazole analogues with potent activity against breast cancer: A design, synthesis, in vitro, and in silico study

MG Salem, DMA El-Maaty, YIM El-Deen, BH Elesawy… - Molecules, 2022 - mdpi.com
Breast cancer is the most common cancer in women, responsible for over half a million
deaths in 2020. Almost 75% of FDA-approved drugs are mainly nitrogen-and sulfur …

Development of Novel 1,3-Disubstituted-2-Thiohydantoin Analogues with Potent Anti-Inflammatory Activity; In Vitro and In Silico Assessments

SM Khirallah, HMM Ramadan, A Shawky, SH Qahl… - Molecules, 2022 - mdpi.com
Inflammation is the main cause of several autoimmune diseases, including type I diabetes,
rheumatoid arthritis, bullous pemphigoid, paraneoplastic pemphigoid, and multiple …

Hepatoprotective role of carvedilol against ischemic hepatitis associated with acute heart failure via targeting MiRNA-17 and mitochondrial dynamics-related proteins …

DI Mohamed, SF Ezzat, WM Elayat, OA El-Kharashi… - Pharmaceuticals, 2022 - mdpi.com
Acute heart failure (AHF) is one of the most common diseases in old age that can lead to
mortality. Systemic hypoperfusion is associated with hepatic ischemia–reperfusion injury …

Unveiling the antitumor potential of novel N-(substituted-phenyl)-8-methoxycoumarin-3-carboxamides as dual inhibitors of VEGFR2 kinase and cytochrome P450 for …

EM Radwan, E Abo-Elabass, AE Abd El-Baky… - Frontiers in …, 2023 - frontiersin.org
Being the sixth most diagnosed cancer and the fourth leading cause of cancer-related
deaths worldwide, liver cancer is considered as a serious disease with a high prevalence …

In Situ Biosynthesis of Reduced Alpha Hematite (α-Fe2O3) Nanoparticles by Stevia Rebaudiana L. Leaf Extract: Insights into Antioxidant, Antimicrobial, and …

SZ Alshawwa, EJ Mohammed, N Hashim, M Sharaf… - Antibiotics, 2022 - mdpi.com
In the present study, we utilized Stevia rebaudiana L.(SRLe) extract to in situ biosynthesize
nanoscale alpha hematite (α-Fe2O3) nanoparticles (NPs) with potent antioxidant …

Antidiabetic potential of novel 1, 3, 5-trisubstituted-2-thioxoimidazloidin-4-one analogues: Insights into α-glucosidase, α-amylase, and antioxidant activities

SM Khirallah, HMM Ramadan, HAA Aladl, NO Ayaz… - Pharmaceuticals, 2022 - mdpi.com
As the ninth leading cause of death globally, diabetes mellitus (DM) is considered to be the
worst chronic metabolic disease requiring an enormous need for healthcare with over 578 …

Development of canagliflozin nanocrystals sublingual tablets in the presence of sodium caprate permeability enhancer: formulation optimization, characterization, in …

S Fathy Elhabal, MA El-Nabarawi, N Abdelaal… - Drug Delivery, 2023 - Taylor & Francis
Canagliflozin (CFZ) is a sodium-glucose cotransporter-2 inhibitor (SGLT2) that lowers
albuminuria in type-2 diabetic patients, cardiovascular, kidney, and liver disease. CFZ is …

Diversity of toxigenic fungi in livestock and poultry feedstuffs

E Khalifa, MT Mohesien, MI Mossa… - International Journal of …, 2022 - mdpi.com
The purpose of this study was to discover how abundant toxigenic fungi and mycotoxins are
in animal feedstuff samples. A total of ninety samples representing various types of animal …