Roadmap: helium ion therapy

A Mairani, S Mein, E Blakely, J Debus… - Physics in Medicine …, 2022 - iopscience.iop.org
Helium ion beam therapy for the treatment of cancer was one of several developed and
studied particle treatments in the 1950s, leading to clinical trials beginning in 1975 at the …

[HTML][HTML] Prompt-gamma fall-off estimation with C-ion irradiation at clinical energies, using a knife-edge slit camera: A Monte Carlo study

A Missaglia, A Bourkadi-Idrissi, F Casamichiela… - Physica medica, 2023 - Elsevier
Purpose: In-vivo range verification has been a hot topic in particle therapy since two
decades. Many efforts have been done for proton therapy, while fewer studies were …

PIBS: Proton and ion beam spectroscopy for in vivo measurements of oxygen, carbon, and calcium concentrations in the human body

P Magalhaes Martins, R Dal Bello, B Ackermann… - Scientific reports, 2020 - nature.com
Proton and ion beam therapy has proven to benefit tumour control with lower side-effects,
mostly in paediatrics. Here we demonstrate a feasible technique for proton and ion beam …

Real-time PET imaging for range verification of helium radiotherapy

I Ozoemelam, E Van der Graaf, MJ Van Goethem… - Frontiers in …, 2020 - frontiersin.org
Real-time range verification of particle beams is important for optimal exploitation of the
tissue-sparing advantages of particle therapy. Positron Emission Tomography (PET) of the …

Prompt gamma spectroscopy for absolute range verification of 12C ions at synchrotron-based facilities

R Dal Bello, PM Martins, S Brons… - Physics in Medicine …, 2020 - iopscience.iop.org
The physical range uncertainty limits the exploitation of the full potential of charged particle
therapy. In this work, we face this issue aiming to measure the absolute Bragg peak position …

Towards real-time PGS range monitoring in proton therapy of prostate cancer

P Magalhaes Martins, H Freitas, T Tessonnier… - Scientific reports, 2021 - nature.com
Proton therapy of prostate cancer (PCPT) was linked with increased levels of gastrointestinal
toxicity in its early use compared to intensity-modulated radiation therapy (IMRT). The higher …

First experimental demonstration of real-time neutron capture discrimination in helium and carbon ion therapy

M Kielly, A Caracciolo, A Chacon, J Vohradsky… - Scientific Reports, 2024 - nature.com
This work provides the first experimental proof of an increased neutron capture photon
signal following the introduction of boron to a PMMA phantom during helium and carbon ion …

A single-particle trigger for time-of-flight measurements in prompt-gamma imaging

P Magalhaes Martins, R Dal Bello, M Seimetz… - Frontiers in …, 2020 - frontiersin.org
Tracking of single particles accelerated by synchrotrons is a subject that crosses several
physics fields. The high clinical intensities used in particle therapy that can exceed 109 p/s …

Prompt gamma imaging system in particle therapy: a mini-review

BW Cheon, CH Min - Frontiers in Physics, 2024 - frontiersin.org
Accurate in-vivo verification of beam range and dose distribution is crucial for the safety and
effectiveness of particle therapy. Prompt gamma (PG) imaging, as a method for real-time …

MC TRIM Algorithm in Mandibula Phantom in Helium Therapy

F Ekinci, K Acici, T Asuroglu, B Emek Soylu - Healthcare, 2023 - mdpi.com
Helium ion beam therapy, one of the particle therapies developed and studied in the 1950s
for cancer treatment, resulted in clinical trials starting at Lawrence Berkeley National …