Biosensors for the detection of bacterial and viral clinical pathogens

L Castillo-Henríquez, M Brenes-Acuña, A Castro-Rojas… - Sensors, 2020 - mdpi.com
Biosensors are measurement devices that can sense several biomolecules, and are widely
used for the detection of relevant clinical pathogens such as bacteria and viruses, showing …

[HTML][HTML] Hemorrhagic fever with renal syndrome: literature review, epidemiology, clinical picture and pathogenesis

M Tariq, DM Kim - Infection & chemotherapy, 2022 - ncbi.nlm.nih.gov
Hantaviruses can cause two types of infections in humans: hemorrhagic fever with renal
syndrome (HFRS) and hantavirus pulmonary syndrome. The old world hantaviruses …

Soluble urokinase receptor (SuPAR) in COVID-19–related AKI

TU Azam, HR Shadid, P Blakely… - Journal of the …, 2020 - journals.lww.com
Background AKI commonly occurs in patients with coronavirus disease 2019 (COVID-19). Its
pathogenesis is poorly understood. The urokinase receptor system is a key regulator of the …

Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody

E Mittler, A Serris, ES Esterman, C Florez… - Science translational …, 2023 - science.org
Emerging rodent-borne hantaviruses cause severe diseases in humans with no approved
vaccines or therapeutics. We recently isolated a monoclonal broadly neutralizing antibody …

[HTML][HTML] Endothelial cells in emerging viral infections

JH Fosse, G Haraldsen, K Falk… - Frontiers in cardiovascular …, 2021 - frontiersin.org
There are several reasons to consider the role of endothelial cells in COVID-19 and other
emerging viral infections. First, severe cases of COVID-19 show a common breakdown of …

[PDF][PDF] The hantavirus surface glycoprotein lattice and its fusion control mechanism

A Serris, R Stass, EA Bignon, NA Muena… - Cell, 2020 - cell.com
Hantaviruses are rodent-borne viruses causing serious zoonotic outbreaks worldwide for
which no treatment is available. Hantavirus particles are pleomorphic and display a …

Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses

E Mittler, AZ Wec, J Tynell, P Guardado-Calvo… - Science translational …, 2022 - science.org
The rodent-borne hantavirus Puumala virus (PUUV) and related agents cause hemorrhagic
fever with renal syndrome (HFRS) in humans. Other hantaviruses, including Andes virus …

Recent advances in bunyavirus glycoprotein research: precursor processing, receptor binding and structure

RJG Hulswit, GC Paesen, TA Bowden, X Shi - Viruses, 2021 - mdpi.com
The Bunyavirales order accommodates related viruses (bunyaviruses) with segmented,
linear, single-stranded, negative-or ambi-sense RNA genomes. Their glycoproteins form …

Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody

R Stass, TB Engdahl, NS Chapman, RM Wolters… - Nature …, 2023 - nature.com
Rodent-borne hantaviruses are prevalent worldwide and upon spillover to human
populations, cause severe disease for which no specific treatment is available. A potent …

A Look into Bunyavirales Genomes: Functions of Non-Structural (NS) Proteins

SS Leventhal, D Wilson, H Feldmann, DW Hawman - Viruses, 2021 - mdpi.com
In 2016, the Bunyavirales order was established by the International Committee on
Taxonomy of Viruses (ICTV) to incorporate the increasing number of related viruses across …