Mn-based MRI contrast agents: an overview

C Henoumont, M Devreux, S Laurent - Molecules, 2023 - mdpi.com
MRI contrast agents are required in the clinic to detect some pathologies, such as cancers.
Nevertheless, at the moment, only small extracellular and non-specific gadolinium …

Endogenous and exogenous antioxidants as agents preventing the negative effects of contrast media (contrast-induced nephropathy)

IG Panova, AS Tatikolov - Pharmaceuticals, 2023 - mdpi.com
The use of conventional contrast media for diagnostic purposes (in particular, Gd-containing
and iodinated agents) causes a large number of complications, the most common of which is …

Chelating ligand-bridged IO-Gd nanoparticles with enhanced contrast performance for dual-mode MRI

L Hao, H Ding, X Xu, H Mao, Z Gu - Journal of Materials Science & …, 2024 - Elsevier
Magnetic resonance imaging (MRI) is a non-invasive medical imaging technique that has
been widely applied in the clinical diagnosis of diseases across various fields. Currently …

Multiple Bioimaging Applications Based on the Excellent Properties of Nanodiamond: A Review

X Wang, D Sang, L Zou, S Ge, Y Yao, J Fan, Q Wang - Molecules, 2023 - mdpi.com
Nanodiamonds (NDs) are emerging as a promising candidate for multimodal bioimaging on
account of their optical and spectroscopic properties. NDs are extensively utilized for …

Expanding Mn2+ loading capacity of BSA via mild non-thermal denaturing and cross-linking as a tool to maximize the relaxivity of water protons

RR Zairov, TA Kornev, BS Akhmadeev… - International Journal of …, 2024 - Elsevier
Abstract Development of nanoparticles (NPs) serving as contrast enhancing agents in MRI
requires a combination of high contrasting effect with the biosafety and hemocompatibility …

Mn-Based Methacrylated Gellan Gum Hydrogels for MRI-Guided Cell Delivery and Imaging

S Vieira, P Strymecka, L Stanaszek, J Silva-Correia… - Bioengineering, 2023 - mdpi.com
This work aims to engineer a new stable injectable Mn-based methacrylated gellan gum
(Mn/GG-MA) hydrogel for real-time monitored cell delivery into the central nervous system …

A Review on the Design of Carbon-Based Nanomaterials as MRI Contrast Agents

S Garifo, T Vangijzegem, D Stanicki, S Laurent - Molecules, 2024 - mdpi.com
The administration of magnetic resonance imaging (MRI) contrast agents (CAs) has been
conducted since 1988 by clinicians to enhance the clarity and interpretability of MR images …

Advances in Manganese-based nanomaterials for cancer therapy via regulating Non-Ferrous ferroptosis

D Kusi, Y Sun, C Liu - International Journal of Pharmaceutics, 2024 - Elsevier
Ferroptosis, a regulated form of cell death distinct from apoptosis, was first identified in 2012
and is characterized by iron-dependent lipid peroxidation driven by reactive oxygen species …

Nanodiamonds in biomedical research: Therapeutic applications and beyond

E Alexander, KW Leong - PNAS Nexus, 2024 - academic.oup.com
Nanodiamonds (NDs) comprise a family of carbon-based nanomaterials (ie, diameter< 100
nm) with the same sp3 lattice structure that gives natural diamonds their exceptional …

Surface engineered nanodiamonds: mechanistic intervention in biomedical applications for diagnosis and treatment of cancer

T Dey, A Ghosh, A Sanyal, CJ Charles… - Biomedical …, 2024 - iopscience.iop.org
In terms of biomedical tools, nanodiamonds (ND) are a more recent innovation. Their size
typically ranges between 4 to 100 nm. ND are produced via a variety of methods and are …