Pneumonia-induced inflammation, resolution and cardiovascular disease: causes, consequences and clinical opportunities

C Stotts, VF Corrales-Medina, KJ Rayner - Circulation research, 2023 - Am Heart Assoc
Pneumonia is inflammation in the lungs, which is usually caused by an infection. The
symptoms of pneumonia can vary from mild to life-threatening, where severe illness is often …

Specialized pro-resolving mediators as modulators of immune responses

WA Julliard, YPA Myo, A Perelas, PD Jackson… - Seminars in …, 2022 - Elsevier
Specialized pro-resolving mediators (SPMs) are endogenous small molecules produced
mainly from dietary omega-3 polyunsaturated fatty acids by both structural cells and cells of …

Crystalline silica-induced proinflammatory eicosanoid storm in novel alveolar macrophage model quelled by docosahexaenoic acid supplementation

OK Favor, LD Rajasinghe, KA Wierenga… - Frontiers in …, 2023 - frontiersin.org
Introduction Phagocytosis of inhaled crystalline silica (cSiO2) particles by tissue-resident
alveolar macrophages (AMs) initiates generation of proinflammatory eicosanoids derived …

The role of omega-3 polyunsaturated fatty acids in the intensive care unit

P Singer, PC Calder - Current Opinion in Clinical Nutrition & …, 2023 - journals.lww.com
The role of omega-3 polyunsaturated fatty acids in the inten... : Current Opinion in Clinical
Nutrition & Metabolic Care The role of omega-3 polyunsaturated fatty acids in the intensive …

Is there a role for specialized pro-resolving mediators in pulmonary fibrosis?

TH Thatcher, MAT Freeberg, YPA Myo… - Pharmacology & …, 2023 - Elsevier
Pulmonary fibrotic diseases are characterized by proliferation of lung fibroblasts and
myofibroblasts and excessive deposition of extracellular matrix proteins. Depending on the …

Application of precision-cut lung slices as an in vitro model for research of inflammatory respiratory diseases

Y Liu, P Wu, Y Wang, Y Liu, H Yang, G Zhou, X Wu… - Bioengineering, 2022 - mdpi.com
The leading cause of many respiratory diseases is an ongoing and progressive
inflammatory response. Traditionally, inflammatory lung diseases were studied primarily …

Cancer treatments as paradoxical catalysts of tumor awakening in the lung

E Nicolas, B Kosmider, E Cukierman… - Cancer and Metastasis …, 2024 - Springer
Much of the fatality of tumors is linked to the growth of metastases, which can emerge
months to years after apparently successful treatment of primary tumors. Metastases arise …

Inflammation resolution and specialized pro-resolving lipid mediators in chronic rhinosinusitis

PZ Robinson, DN Frank… - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction In chronic rhinosinusitis (CRS), a complex pathophysiology results from varied
pro-inflammatory stimuli but is consistently characterized by classic cellular, molecular, and …

Friend or foe? Inflammation and the foreign body response to orthopedic biomaterials

E Gibon, Y Takakubo, S Zwingenberger… - … Research Part A, 2024 - Wiley Online Library
The use of biomaterials and implants for joint replacement, fracture fixation, spinal
stabilization and other orthopedic indications has revolutionized patient care by reliably …

Proposition of a new POLA index to assess the immunomodulatory properties of the diet and its relationship with the gut microbiota, using the example of the …

P Jagielski, D Wnęk, E Łuszczki, I Bolesławska… - Nutrients, 2022 - mdpi.com
A rise in the incidence of infections with severe acute respiratory syndrome coronavirus 2
has sparked the search for protective strategies against the new pathogen. It is known that …