Self-driving laboratories for chemistry and materials science

G Tom, SP Schmid, SG Baird, Y Cao, K Darvish… - Chemical …, 2024 - ACS Publications
Self-driving laboratories (SDLs) promise an accelerated application of the scientific method.
Through the automation of experimental workflows, along with autonomous experimental …

[HTML][HTML] Automated liquid-handling operations for robust, resilient, and efficient bio-based laboratory practices

MA Torres-Acosta, GJ Lye, D Dikicioglu - Biochemical Engineering Journal, 2022 - Elsevier
Increase in the adoption of liquid handling devices (LHD) can facilitate experimental
activities. Initially adopted by businesses and industry-based laboratories, the practice has …

Open hardware: From DIY trend to global transformation in access to laboratory equipment

T Wenzel - PLoS Biology, 2023 - journals.plos.org
Open hardware solutions are increasingly being chosen by researchers as a strategy to
improve access to technology for cutting-edge biology research. The use of DIY technology …

Physical laboratory automation in synthetic biology

A Stephenson, L Lastra, B Nguyen, YJ Chen… - ACS Synthetic …, 2023 - ACS Publications
Synthetic Biology has overcome many of the early challenges facing the field and is entering
a systems era characterized by adoption of Design-Build-Test-Learn (DBTL) approaches …

Transforming science labs into automated factories of discovery

A Angelopoulos, JF Cahoon, R Alterovitz - Science Robotics, 2024 - science.org
Laboratories in chemistry, biochemistry, and materials science are at the leading edge of
technology, discovering molecules and materials to unlock capabilities in energy, catalysis …

Sidekick: a low-cost open-source 3D-printed liquid dispensing robot

R Keesey, R LeSuer, J Schrier - HardwareX, 2022 - Elsevier
The Sidekick is a desktop liquid dispenser, compatible with standard SBS microplates and
designed for accessible laboratory automation. It features an armature-based motion system …

NfκB signaling dynamics and their target genes differ between mouse blood cell types and induce distinct cell behavior

T Kull, A Wehling, M Etzrodt, M Auler… - Blood, The Journal …, 2022 - ashpublications.org
Cells can use signaling pathway activity over time (ie, dynamics) to control cell fates.
However, little is known about the potential existence and function of signaling dynamics in …

Integrating a Pipette Into a Robot Manipulator With Uncalibrated Vision and TCP for Liquid Handling

J Zhang, W Wan, N Tanaka, M Fujita… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
This paper presents a system integration approach for a 6-DoF (Degree of Freedom)
collaborative robot to operate a pipette for liquid dispensing. Its technical development is …

Recent Advances in High-Content Imaging and Analysis in iPSC-Based Modelling of Neurodegenerative Diseases

G Menduti, M Boido - International Journal of Molecular Sciences, 2023 - mdpi.com
In the field of neurodegenerative pathologies, the platforms for disease modelling based on
patient-derived induced pluripotent stem cells (iPSCs) represent a valuable molecular …

Inkube: An all-in-one solution for neuron culturing, electrophysiology, and fluidic exchange

B Maurer, S Fassbind, T Ruff, J Duru, G Spacone… - bioRxiv, 2024 - biorxiv.org
Culturing neuronal networks in vitro is a tedious and time-consuming endeavor. In addition,
how the composition of the culture medium and environmental variables such as …