Citrobacter rodentium is an extracellular enteric mouse-specific pathogen used to model
infections with human pathogenic Escherichia coli and inflammatory bowel disease. C …

Non-vitamin K oral anticoagulants (NOACs) have revolutionized anticoagulant therapy,
offering improved safety and efficacy over traditional agents like warfarin. This review …

Inflammatory diseases have become increasingly prevalent throughout the world.
Coronavirus disease 2019 (COVID‐19), which has recently become pandemic, also exhibits …

Excessive activation of the thrombin receptor, protease activated receptor 1 (PAR1) is
implicated in diverse neuropathologies from neurodegenerative conditions to neurotrauma …

The activation and mobilization of immune cells play a crucial role in immunotherapy.
Existing therapeutic interventions, such as cytokines administration, aim to enhance immune …

Type-17 immune response, mediated mainly by IL-17, plays a critical role in ulcerative
colitis. Previously, we showed that madecassic acid (MA), the main active ingredient of …

Inflammatory bowel disease (IBD) is a chronic, recurrent inflammatory disease caused by
the destruction of the intestinal mucosal epithelium that affects a growing number of people …

Colorectal cancer (CRC) is one of the common malignancies with a global trend of
increasing incidence and mortality. There is an urgent need to identify new predictive …

Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with excessive
inflammation and defective skin barrier function. Activated protein C (APC) is a natural …

Crohn's disease [CD] and ulcerative colitis [UC] are the two main forms of inflammatory
bowel disease [IBD]. Previous studies reported increased levels of proteolytic activity in stool …