Ever since the discovery of vaccines, many deadly diseases have been contained
worldwide, ultimately culminating in the eradication of smallpox and polio, which …

It is evident that the emergence of infectious diseases, which have the potential for spillover
from animal reservoirs, pose an ongoing threat to global health. Zoonotic transmission …

The transmission of influenza A viruses (IAVs) from animal to human has resulted in a
number of pandemics. Here, we report the synthesis of several sialyl-glycan-functionalized …

The recent outbreak of Zika virus (ZIKV) has emerged as a global health concern. ZIKV can
persist in human semen and be transmitted by sexual contact, as well as by mosquitoes, as …

Background Respiratory syncytial virus (RSV) disease is a major cause of infant morbidity
and mortality. This Phase I, randomized, observer-blind, placebo-and active-controlled study …

Since the development of the first vaccine against smallpox over two centuries ago,
vaccination strategies have been at the forefront of significantly impacting the incidences of …

Adenoviral vectors have been widely used as vaccine candidates or potential vaccine
candidates against infectious diseases due to the convenience of genome manipulation …

Vaccines are essential tools to prevent infection and control transmission of infectious
diseases that threaten public health. Most infectious agents enter their hosts across mucosal …

Introduction: In recent years, replication-defective chimpanzee-derived adenoviruses have
been extensively evaluated as genetic vaccines. These vectors share desirable properties …

Recombinant adenovirus vectors have been widely used in vaccine development. To
overcome the preexisting immunity of human adenovirus type 5 (Ad5) in populations, a …