Given their potential in a better characterization and diagnosis of major pathologies like
cancer or chronic inflammation, redox-activated Magnetic Resonance Imaging (MRI) probes …

The reduction/oxidation (redox) potential of tissue is tightly regulated in order to maintain
normal physiological processes, but is disrupted in disease states. Thus, the development of …

Fe (III) complexes are attracting growing interest in chemists developing diagnostic probes
for Magnetic Resonance Imaging because they leverage on an endogenous metal and …

Transition-metal-ion-based paramagnetic chemical exchange saturation transfer
(paraCEST) agents are a promising new class of compounds for magnetic resonance …

The first examples of air-stable CoII paraCEST MRI contrast agents are reported. Amide NH
protons on the complexes give rise to CEST peaks that are shifted up to 112 ppm from the …

Paramagnetic Ni (II) complexes are shown here to form paraCEST MRI contrast agents
(paraCEST= paramagnetic chemical exchange saturation transfer; NiCEST= Ni (II) based …

We report a Co2-based magnetic resonance (MR) probe that enables the ratiometric
quantitation and imaging of pH through chemical exchange saturation transfer (CEST). This …

The development of responsive or “smart” magnetic resonance imaging (MRI) contrast
agents that can report specific biomarker or biological events has been the focus of MRI …

We report the synthesis of the ligand Hnompa (6-((1, 4, 7-triazacyclononan-1-yl) methyl)
picolinic acid) and a detailed characterization of the Mn2+ complexes formed by this ligand …

Accurate mapping of small changes in pH is essential to the diagnosis of diseases such as
cancer. The difficulty in mapping pH accurately in vivo resides in the need for the probe to …