[HTML][HTML] Significance of RAS mutations in thyroid benign nodules and non-medullary thyroid cancer

V Marotta, M Bifulco, M Vitale - Cancers, 2021 - mdpi.com
Simple Summary Only about 4% of thyroid nodules are carcinomas and require surgery.
Fine-needle aspiration cytology is the most accurate tool to distinguish benign from …

Molecular testing for indeterminate thyroid nodules: past, present, and future

R Raghunathan, SS Praw, M Livhits - Current Opinion in …, 2023 - journals.lww.com
Molecular testing of indeterminate thyroid nodules has helped to reduce the burden of
diagnostic surgery, associated healthcare costs, and potential complications. Current …

Transoral thyroidectomy: a viable surgical option with unprecedented complications—a case series

S Bakkar, M Al Hyari, M Naghawi, C Corsini… - Journal of …, 2018 - Springer
Purpose To report the clinical implications of an initial experience with transoral endoscopic
thyroidectomy vestibular approach (TOETVA). Methods From March to November 2017, five …

[HTML][HTML] Diagnostic performance of ATA, BTA and TIRADS sonographic patterns in the prediction of malignancy in histologically proven thyroid nodules

CL Chng, HC Tan, CW Too, WY Lim… - Singapore medical …, 2018 - ncbi.nlm.nih.gov
METHODS Thyroid nodules measuring> 1 cm resected over 5.5 years were retrospectively
studied. Demographic information as well as cytology and histopathology results were …

Malignancy Risk of Follicular Neoplasm (Bethesda IV) With Variable Cutoffs of Tumor Size: A Systemic Review and Meta-Analysis

YY Cho, SH Ahn, EK Lee, YJ Park… - The Journal of …, 2024 - academic.oup.com
Context The decision on diagnostic lobectomy for follicular neoplasms (FN) is challenging.
Objective This meta-analysis investigates whether an appropriate size cutoff exists for …

[HTML][HTML] Frequency and Significance of Ras, Tert Promoter, and Braf Mutations in Cytologically Indeterminate Thyroid Nodules: A Monocentric Case Series at a …

S Censi, E Cavedon, L Bertazza, F Galuppini… - Frontiers in …, 2017 - frontiersin.org
Purpose The management of thyroid nodules of indeterminate cytology is controversial. Our
study aimed to establish the frequency and significance of H-, K-, N-RAS, TERT promoter …

[HTML][HTML] Correlations between molecular landscape and sonographic image of different variants of papillary thyroid carcinoma

A Lewiński, Z Adamczewski, A Zygmunt… - Journal of clinical …, 2019 - mdpi.com
Papillary thyroid carcinoma (PTC), the most common thyroid cancer, is predominantly driven
by mutations in BRAF (primarily p. V600E) and RAS oncogenes. Ultrasound (US) …

Heterogeneity in Positive Predictive Value of RAS Mutations in Cytologically Indeterminate Thyroid Nodules

F Nabhan, K Porter, MA Lupo, GW Randolph, KN Patel… - Thyroid, 2018 - liebertpub.com
Background: RAS mutations are common in the available mutational analysis of
cytologically indeterminate (Cyto-I) thyroid nodules. However, their reported positive …

Ultrasound characteristics of thyroid nodules facilitate interpretation of the malignant risk of Bethesda system III/IV thyroid nodules and inform therapeutic schedule

F Li, D Pan, Y Wu, J Peng, Q Li, X Gui… - Diagnostic …, 2019 - Wiley Online Library
Background This study was designed to explore whether ultrasound of thyroid nodules
facilitates the interpretation of the malignant risk of Bethesda III/IV thyroid nodules to inform …

BRAFK601E Mutation in a Follicular Thyroid Adenoma: A Case Report

E Macerola, L Torregrossa, C Ugolini… - … journal of surgical …, 2017 - journals.sagepub.com
BRAF mutations represent the most common genetic alteration in papillary thyroid
carcinoma (PTC). The p. V600E mutation is specific for the classic and tall-cell variants of …