Alterations in the expression of homologous recombination repair (HRR) genes in breast cancer tissues considering germline BRCA1/2 mutation status

L Izabela, M Rafal, S Stanislaw, K Pawel… - Breast Cancer Research …, 2024 - Springer
Introduction Homologous recombination (HR) is a crucial DNA-repair mechanism, and its
disruption can lead to the accumulation of mutations that initiate and promote cancer …

Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer

Y Jin, X Lu, Y Liu, L Su, C Bao, H Guo - Cytotechnology, 2024 - Springer
CD8+ T cells are the primary mediators of anticancer immunity, and modulation of the CD8+
T cell response has been a central focus of immunotherapy to treat cancer. When CD8+ T …